EFFECTIVE FACTORS ON PORTAL HYPERTENSIVE GASTROPATHY AND DUDENOPATHY IN CIRRHOTIC PATIENTS: TALEGHANI HOSPITAL (1377-1379)

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FAKHRIEH S.; EHSANI ARDAKANI M.J.

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2003 | Volume:7 | Issue:4 Page(s): 322-327

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Title

EFFECTIVE FACTORS ON PORTAL HYPERTENSIVE GASTROPATHY AND DUDENOPATHY IN CIRRHOTIC PATIENTS: TALEGHANI HOSPITAL (1377-1379)

Author(s)

FAKHRIEH S. | EHSANI ARDAKANI M.J. | Issue Writer Certificate

Keywords

CIRRHOSISQ3

PORTAL HYPERTENSIVE GASTROPATHYQ4

PORTAL HYPERTENSIVE DUDENOPATHYQ4

Abstract

Introduction: CIRRHOSIS has pathological specificities representing clinical manifestations. Portal hypertension is a complication of CIRRHOSIS that produces a specific lesion in gastrointestinal system. The most important of these lesions are varices of esophagus and stomach. Other interesting lesions are PORTAL HYPERTENSIVE GASTROPATHY (PHG), PORTAL HYPERTENSIVE DUDENOPATHY (PHD), Jejunopathy, and colopathy PHG and PHD are the causes of 8-20% of gastrointestinal bleeding in patients with portal hypertension. Controversies exist regarding the relationship of PHG and PHD with other factors. Because of many complications of gastrointestinal bleeding in Cirrhotic patients we decided to study the relationship of many factors with PHG and PHD. Methods: In a descriptive analytic study we enrolled 120 cirrhotic patients for whom sclerotherapy had not been done. All data about their personal characteristics, serum albumin, prothrombin time, serum billirubin, etiology of CIRRHOSIS, propranolol consumption, previous or present history of gastrointestinal bleeding were obtained from their charts. Endoscopy was done for all of them and H.pylori status by urease test and histopathology was determined.Results: From 120 patients, 41 (34.2%) were female and 79 (65.8%)were male most of whom were between 50-61 years old. All the patients were in age range of 14-73 years old. Result of correlation analysis didnt show a meaningful relation between PHG and PHD with grading of esophageal varices, varices of stomach, history of gastrointestinal bleeding, sex, age, H.pylori status, childs classification and etiology of CIRRHOSIS. The only indirect meaningful relation was between PHG and propranolol consumption (r=-0.28,p<0.01). The only direct meaningful relation was between PHG and PHD (r=0.443,p<0.01). Discussion: Factor analysis showed a more clear cut relationship amongst variables. Grading of esophageal varices , history of gastrointestinal bleeding and childs classification had the first role of correlation with PHG . Propranolol consumption had a negative direction with PHG. Age, etiology of CIRRHOSIS as a significant collection had an indirect effect on PHD by the route of PHG. H.pylori status and sex had a less important role and we can omit them in the other same study.

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APA: Copy

FAKHRIEH, S., & EHSANI ARDAKANI, M.J.. (2003). EFFECTIVE FACTORS ON PORTAL HYPERTENSIVE GASTROPATHY AND DUDENOPATHY IN CIRRHOTIC PATIENTS: TALEGHANI HOSPITAL (1377-1379). JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 7(4), 322-327. SID. https://sid.ir/paper/26666/en

Vancouver: Copy

FAKHRIEH S., EHSANI ARDAKANI M.J.. EFFECTIVE FACTORS ON PORTAL HYPERTENSIVE GASTROPATHY AND DUDENOPATHY IN CIRRHOTIC PATIENTS: TALEGHANI HOSPITAL (1377-1379). JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2003;7(4):322-327. Available from: https://sid.ir/paper/26666/en

IEEE: Copy

S. FAKHRIEH, and M.J. EHSANI ARDAKANI, “EFFECTIVE FACTORS ON PORTAL HYPERTENSIVE GASTROPATHY AND DUDENOPATHY IN CIRRHOTIC PATIENTS: TALEGHANI HOSPITAL (1377-1379),” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 7, no. 4, pp. 322–327, 2003, [Online]. Available: https://sid.ir/paper/26666/en

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