The Effect of 4 week resistance training on male rat hepatic ABCA1 protein plasma HDL-C levels

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Ganj Khani Leyla; OSALI ALI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY Year:2019 | Volume:6 | Issue:1 Page(s): 22-30

Download Full-Text

Persian Verion

View:

400

Download:

Cites:

Information Journal Paper

Title

The Effect of 4 week resistance training on male rat hepatic ABCA1 protein plasma HDL-C levels

Author(s)

Ganj Khani Leyla | OSALI ALI | Issue Writer Certificate

Keywords

ABCA1

resistance training

HDL-C and apoA-I

Abstract

ABCA1, a member of ABC (ATP-binding cassette transporters) family in mammals plays a fundamental role in HDL-C remodeling and thus prevent atherosclerosis. The purpose of this study was to investigate the changes of hepatic ABCA1 and plasma of HDL-C levels of male Wistar rats following four weeks of resistance training. 16 male Wistar rats with the age of 12-14 weeks and a mean body weight of 290± 10g were used. Rats were divided in Two groups of control (n=8) and exercise (n=8). resistance training consisted of climbing a one meter ladder (26 stairs and 80 degree angle with the ground) with weights tied to the tail of the animal. Finally, rats performed three consecutive sets with 100% of their body weights (6 reps per set). Rats were sacrificed 48 h after the last training session. Sampled Liver tissue, after washing with saline, were immediately frozen by liquid nitrogen. Finally, samples were transferred to-70° C. Blood samples were directly taken from the heart and the plasma were isolated for measurement of the HDL and apoA-I (the major apolipoprotein of HDL). ELISA kit was used to evaluate the amount of ABCA1 and apoA-I and Plasma HDL level was determined by enzymatic immune method. For data analysis, independent T test was used. The results showed that ABCA1 in the liver of rats was higher for about 25 percent higher than the control group, but was not statistically significant. Plasma HDL levels were not significantly different between two groups. Moreover, despite some increases in apoA-I levels they were not statistically significant. Thus, despite the fact that four weeks of resistance training didn’ t make statistically significant changes in ABCA1 and HDL and apoA-I, but according to the trend of the data this resistance training protocol seemed to be partly effective Possibly, better results can be achieved by increasing the intensity and leng of the execises, or by designing a beter combination of exercises.

Cites

The Effect of Combined and Rehabilitation Training on ABCA1 Gene Expression in Blood Lymphocytes and Lipid Profile in Middle-aged Men with Coronary Bypass Graft

References

No record.

Cite

APA: Copy

Ganj Khani, Leyla, & OSALI, ALI. (2019). The Effect of 4 week resistance training on male rat hepatic ABCA1 protein plasma HDL-C levels. JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY, 6(1 ), 22-30. SID. https://sid.ir/paper/269325/en

Vancouver: Copy

Ganj Khani Leyla, OSALI ALI. The Effect of 4 week resistance training on male rat hepatic ABCA1 protein plasma HDL-C levels. JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY[Internet]. 2019;6(1 ):22-30. Available from: https://sid.ir/paper/269325/en

IEEE: Copy

Leyla Ganj Khani, and ALI OSALI, “The Effect of 4 week resistance training on male rat hepatic ABCA1 protein plasma HDL-C levels,” JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY, vol. 6, no. 1 , pp. 22–30, 2019, [Online]. Available: https://sid.ir/paper/269325/en

Related Journal Papers