The Effect of Walking Exercise with Blood Flow Restriction on Mtor Signaling Pathway in Untrained Male Subjects’ Skeletal Muscle

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Hallajbashi Saeid; MIRZAEI BAHMAN; Rahmaniniya Farhad

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Journal: JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY Year:2020 | Volume:6 | Issue:2 Page(s): 9-16

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Title

The Effect of Walking Exercise with Blood Flow Restriction on Mtor Signaling Pathway in Untrained Male Subjects’ Skeletal Muscle

Author(s)

Hallajbashi Saeid | MIRZAEI BAHMAN | Rahmaniniya Farhad | Issue Writer Certificate

Keywords

blood lactate

Kaatsu training

muscle biopsy

muscle hypertrophy

Abstract

The purpose of this study was to study the acute responses to BFR walking exercise on the mTOR signaling pathway in untrained male subjects. five (n=5) apparently healthy untrained male participants were studied identically on two occasions: (1) BFR aerobic exercise consisting of walking at an exercise intensity of 40% VO2max (2) Identical walking exercise without BFR (Ctrl). Each trial was separated by 3 weeks. muscle biopsy (vastus lateralis) and blood sample (antecubital vein) were obtained pre-and post-exercise in given time points to determine protein expression and changes in GH and IGF-1. Results showed that mTOR and p70S6K phosphorylation levels did not change significantly in both groups (P ˃ 0. 05). IGF-1 and GH immediately after exercise increased in BFR group (P˂ 0. 05). blood lactate did not show any significant change in both groups. We find that the phosphorylation of p70S6K and mTOR did not activate after a bout of walking with blood flow restriction. As result the mTOR signaling pathway is not responsible for stimulating skeletal muscle protein synthesis after BFR walking exercise.

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APA: Copy

Hallajbashi, Saeid, MIRZAEI, BAHMAN, & Rahmaniniya, Farhad. (2020). The Effect of Walking Exercise with Blood Flow Restriction on Mtor Signaling Pathway in Untrained Male Subjects’ Skeletal Muscle. JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY, 6(2 ), 9-16. SID. https://sid.ir/paper/269343/en

Vancouver: Copy

Hallajbashi Saeid, MIRZAEI BAHMAN, Rahmaniniya Farhad. The Effect of Walking Exercise with Blood Flow Restriction on Mtor Signaling Pathway in Untrained Male Subjects’ Skeletal Muscle. JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY[Internet]. 2020;6(2 ):9-16. Available from: https://sid.ir/paper/269343/en

IEEE: Copy

Saeid Hallajbashi, BAHMAN MIRZAEI, and Farhad Rahmaniniya, “The Effect of Walking Exercise with Blood Flow Restriction on Mtor Signaling Pathway in Untrained Male Subjects’ Skeletal Muscle,” JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY, vol. 6, no. 2 , pp. 9–16, 2020, [Online]. Available: https://sid.ir/paper/269343/en

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