Kinetic Study of ß-Carotene Degradation in Nanostructured Lipid Carriers

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HEJRI A.; KHOSRAVI A.R.; GHARANJIG K.

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Journal: ADVANCED MATERIALS AND NOVEL COATINGS Year:2019 | Volume:8 | Issue:29 Page(s): 2108-2115

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Information Journal Paper

Title

Kinetic Study of ß-Carotene Degradation in Nanostructured Lipid Carriers

Author(s)

HEJRI A. | KHOSRAVI A.R. | GHARANJIG K. | Issue Writer Certificate

Keywords

Nanostructured Lipid Carriers

-carotene

Degradation

Kinetics

Nanotechnology

Abstract

In this research, Degradation of ß;-carotene in Nanostructured Lipid Carriers was studied employing spectrophotometric method. The effect of ß;-carotene concentration, liquid lipid concentration, surfactant concentration and temperature on stability of ß;-carotene was investigated. ß;-carotene loaded Nanostructured Lipid Carriers were prepared using solvent diffusion method and the samples were kept in darkness at room temperature. The results indicated that the Degradation of ß;-carotene in Nanostructured Lipid Carriers follows first order Kinetics. The stability of ß;-carotene increased significantly by increasing the liquid oil concentration. Furthermore, rising the ß;-carotene and surfactant concentrations from 1 to 5 %w/w resulted in climbing of Degradation rate constants from 0. 00473 and 0. 00737 up to 0. 01280 and 0. 01093 1/h, respectively. ß;-carotene retention decreased by Increment of temperature from 5° C to 65° C while further elevating of temperature was led to reverse results. Particle size studies revealed that addition of ß;-carotene to Nanostructured Lipid Carriers grows particle size from 38nm to 105 nm. Moreover, liquid lipid concentration had no significant effect on initial particle size of ß;-carotene loaded Nanostructured Lipid Carriers.

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APA: Copy

HEJRI, A., KHOSRAVI, A.R., & GHARANJIG, K.. (2019). Kinetic Study of ß-Carotene Degradation in Nanostructured Lipid Carriers. ADVANCED MATERIALS AND NOVEL COATINGS, 8(29 ), 2108-2115. SID. https://sid.ir/paper/270223/en

Vancouver: Copy

HEJRI A., KHOSRAVI A.R., GHARANJIG K.. Kinetic Study of ß-Carotene Degradation in Nanostructured Lipid Carriers. ADVANCED MATERIALS AND NOVEL COATINGS[Internet]. 2019;8(29 ):2108-2115. Available from: https://sid.ir/paper/270223/en

IEEE: Copy

A. HEJRI, A.R. KHOSRAVI, and K. GHARANJIG, “Kinetic Study of ß-Carotene Degradation in Nanostructured Lipid Carriers,” ADVANCED MATERIALS AND NOVEL COATINGS, vol. 8, no. 29 , pp. 2108–2115, 2019, [Online]. Available: https://sid.ir/paper/270223/en

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