FACTORS AFFECTING SURVIVAL IN KIDNEY RECIPIENTS AT KERMANSHAH

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REZAEE M.; KAZEMNEJAD ANOUSHIRAVAN; BARDIDEH AR.; MAHMOUDI M.

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Journal: UROLOGY JOURNAL Year:2004 | Volume:1 | Issue:3 Page(s): 180-187

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Title

FACTORS AFFECTING SURVIVAL IN KIDNEY RECIPIENTS AT KERMANSHAH

Author(s)

REZAEE M. | KAZEMNEJAD ANOUSHIRAVAN | BARDIDEH AR. | MAHMOUDI M. | Issue Writer Certificate

Keywords

KIDNEY TRANSPLANTATION

SURVIVAL RATE

COX REGRESSION

AFFECTING FACTOR

LOG RANK TEST

Abstract

Purpose: To evaluate patient and graft survivals in kidney recipients and factors impacting on SURVIVAL RATEs at Kermanshah. Materials and Methods: This study was done on 712 kidney transplants from 1989 through 2001 in Kermanshah. One of the most important applications of survival analysis is assessing the role of explanatory factors in the studied event. In this study Kaplan-Meier method was used to calculate patient and graft survivals and in order to determine the factors affecting survival, Cox proportional hazard model was used. The iterations in Cox model was four times and the inclusion and exclusion criteria, calculated by forward conditional method were less than 5% and 10%, respectively. Results: Of the recipients, 47.6%were female and most of them (94.4%) had received kidneys from living unrelated donors. One-year patient survivals in recipients from living unrelated donors (LURD) and living related donors (LRD) were 89.4% and 100%, 3-year survivals were 82% and 97.4%, and lO-year survivals were 61.4% and 72%,respectively. In addition, graft SURVIVAL RATEs in one year were 85.6% and 97.4%, in three years were 77.2%and 92.3%, and in 10 years were 33.3% and 60.6% in LURD and LRD, respectively. In Cox model, four factors, including the presence of surgical or other complications, known primary disease, and donor-recipient relationship had significant association with patient survival and seven factors, including the presence of surgical complications, known primary disease, donor-recipient relationship, gender, weight, same side transplanted kidney, and donors age had significant relationship with graft survival. Conclusion: In summary, it can be concluded that patient and donor demographic characteristics and transplantation conditions may affect patient and graft survival. With the use of multtvariate regression analysis methods, the characteristics that have high probability for survival can be determined. Controlling these situations, where they have high survival probability, effectively help better treatment and high SURVIVAL RATE.

Cites

RISK FACTORS OF GRAFT SURVIVAL AFTER DIAGNOSIS OF POST-KIDNEY TRANSPLANT MALIGNANCY: USING COX PROPORTIONAL HAZARD MODEL

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APA: Copy

REZAEE, M., KAZEMNEJAD, ANOUSHIRAVAN, BARDIDEH, AR., & MAHMOUDI, M.. (2004). FACTORS AFFECTING SURVIVAL IN KIDNEY RECIPIENTS AT KERMANSHAH. UROLOGY JOURNAL, 1(3), 180-187. SID. https://sid.ir/paper/270658/en

Vancouver: Copy

REZAEE M., KAZEMNEJAD ANOUSHIRAVAN, BARDIDEH AR., MAHMOUDI M.. FACTORS AFFECTING SURVIVAL IN KIDNEY RECIPIENTS AT KERMANSHAH. UROLOGY JOURNAL[Internet]. 2004;1(3):180-187. Available from: https://sid.ir/paper/270658/en

IEEE: Copy

M. REZAEE, ANOUSHIRAVAN KAZEMNEJAD, AR. BARDIDEH, and M. MAHMOUDI, “FACTORS AFFECTING SURVIVAL IN KIDNEY RECIPIENTS AT KERMANSHAH,” UROLOGY JOURNAL, vol. 1, no. 3, pp. 180–187, 2004, [Online]. Available: https://sid.ir/paper/270658/en

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