EFFECT OF SAFFRON ON SEMEN PARAMETERS OF INFERTILE MEN

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HEYDARI MOHAMMAD; REZANEZHADI JAHAN BAKHSH; DELFAN B.; BIRJANDI M.; KAVIANI HOSSEIN; GIVRAD S.

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Journal Paper

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Journal: UROLOGY JOURNAL Year:2008 | Volume:5 | Issue:4 Page(s): 255-259

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Information Journal Paper

Title

EFFECT OF SAFFRON ON SEMEN PARAMETERS OF INFERTILE MEN

Author(s)

Keywords

MALE INFERTILITY

CROCUS SATIVUS

ANTIOXIDANTS

SPERM MOTILITY

SPERM COUNT

Abstract

Introduction: We conducted this study to determine the effects of saffron (Crocus sativus) on the results of semen analysis in men with idiopathic infertility. Materials and Methods: In this clinical trial, 52 nonsmoker infertile men whose problem could not be solved surgically were enrolled. They were treated by saffron for 3 months. Saffron, 50 mg, was solved in drinking milk and administered 3 times a week during the study course. Semen analysis was done before and after the treatment and the results were compared. Results: The mean percentage of sperm with normal morphology was 26.50±6.44% before the treatment which increased to 33.90±10.45%, thereafter (P<.001). The mean percentage of sperm with Class A motility was 5.32±4.57% before and 11.77±6.07% after the treatment (P<.001). Class B and C motilities were initially 10.09±4.20% and 19.79±9.11% which increased to 17.92±6.50% (P<.001) and 25.35±10.22% (P<.001), respectively. No significant increase was detected in SPERM COUNT; the mean SPERM COUNT was 43.45±31.29x106/mL at baseline and 44.92±28.36x106/mL after the treatment period (P=.30).Conclusion: Saffron, as an antioxidant, is positively effective on sperm morphology and motility in infertile men, while it does not increase SPERM COUNT. We believe further studies on larger sample sizes are needed to elucidate the potential role and mechanism of action of saffron and its ingredient in the treatment of MALE INFERTILITY.

Cites

THE STUDY OF ANTI GENOTOXIC EFFECTS OF SAFFRON AQUEOUS EXTRACT IN CADMIUM CHLORIDE EXPOSED MICE KIDNEY BY COMET ASSAY

References

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APA: Copy

HEYDARI, MOHAMMAD, REZANEZHADI, JAHAN BAKHSH, DELFAN, B., BIRJANDI, M., KAVIANI, HOSSEIN, & GIVRAD, S.. (2008). EFFECT OF SAFFRON ON SEMEN PARAMETERS OF INFERTILE MEN. UROLOGY JOURNAL, 5(4), 255-259. SID. https://sid.ir/paper/270860/en

Vancouver: Copy

HEYDARI MOHAMMAD, REZANEZHADI JAHAN BAKHSH, DELFAN B., BIRJANDI M., KAVIANI HOSSEIN, GIVRAD S.. EFFECT OF SAFFRON ON SEMEN PARAMETERS OF INFERTILE MEN. UROLOGY JOURNAL[Internet]. 2008;5(4):255-259. Available from: https://sid.ir/paper/270860/en

IEEE: Copy

MOHAMMAD HEYDARI, JAHAN BAKHSH REZANEZHADI, B. DELFAN, M. BIRJANDI, HOSSEIN KAVIANI, and S. GIVRAD, “EFFECT OF SAFFRON ON SEMEN PARAMETERS OF INFERTILE MEN,” UROLOGY JOURNAL, vol. 5, no. 4, pp. 255–259, 2008, [Online]. Available: https://sid.ir/paper/270860/en

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