Does the New Proposal for Prostate Cancer Grading Correlate With CAPRA Score?

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Isikay Levent; Tonyali Senol; Aydog Gulden

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Journal Paper

Paper Information

Journal: UROLOGY JOURNAL Year:2018 | Volume:15 | Issue:6 Page(s): 355-358

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Information Journal Paper

Title

Does the New Proposal for Prostate Cancer Grading Correlate With CAPRA Score?

Author(s)

Isikay Levent | Tonyali Senol | Aydog Gulden | Issue Writer Certificate

Keywords

biochemical recurrence

CAPRA

Gleason pattern

pathologic examination

prostatectomy

Abstract

Purpose: To determine if there is a correlation between the newly proposed Gleason grading system by the International Society of Urological Pathology and the Cancer of the Prostate Risk Assessment (CAPRA) score. Material and Methods: The records of all patients that underwent radical prostatectomy at our hospital between 2007 and 2013 were retrospectively reviewed. The study parameters included patient demographics, the percentage of pre-operative prostate biopsies positive for PCa, biopsy Gleason Score (GS), and pre-and post-operative PSA values. Result: The study included 146 patients with complete medical records and follow-up data. Mean age of the patients was 66. 6 ± 6. 08 years. According to the newly proposed Gleason grading system, 97 (66. 4%) patients were grade 1, 20 (13. 7%) were grade 2, 8 (5. 5%) were grade 3, 11 (7. 5%) were grade 4, and 10 (6. 8%) were grade 5. The distribution of CAPRA scores was as follows: 1: n = 43 (29. 5%); 2: n = 53 (36. 3%); 3: n = 22 (15. 1%); 4: n = 14 (9. 6%); 5: n = 8 (5. 5%); 6: n = 4 (2. 7%); 7: n = 1 (0. 7%); 8: n = 1 (0. 7%). Correlation analysis showed that the CAPRA score was significantly correlated with GS based on the newly proposed Gleason grading system (Correlation Coefficient=0. 361, P < 0. 001). Conclusion: As a strong correlation was noted between these 2 independent grading systems, we think clinicians that seek to predict the prognosis in PCa patients should take into consideration both the newly proposed ISUP grading system and the CAPRA score.

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APA: Copy

Isikay, Levent, Tonyali, Senol, & Aydog, Gulden. (2018). Does the New Proposal for Prostate Cancer Grading Correlate With CAPRA Score?. UROLOGY JOURNAL, 15(6), 355-358. SID. https://sid.ir/paper/271252/en

Vancouver: Copy

Isikay Levent, Tonyali Senol, Aydog Gulden. Does the New Proposal for Prostate Cancer Grading Correlate With CAPRA Score?. UROLOGY JOURNAL[Internet]. 2018;15(6):355-358. Available from: https://sid.ir/paper/271252/en

IEEE: Copy

Levent Isikay, Senol Tonyali, and Gulden Aydog, “Does the New Proposal for Prostate Cancer Grading Correlate With CAPRA Score?,” UROLOGY JOURNAL, vol. 15, no. 6, pp. 355–358, 2018, [Online]. Available: https://sid.ir/paper/271252/en

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