UROLOGICAL ONCOLOGY: The Effect of Phosphodiesterase 5 Inhibitor on Biochemical Recurrence Following Radical Prostatectomy in Patients with Prostate Cancer

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Chung Jae Wook; Kim Jin Woo; Ha Yun Sok; Choi Seock Hwan; Lee Jun Nyung; Kim Bum Soo; Kim Hyun Tae; Yoo Eun Sang; Kwon Tae Gyun; Kim Tae Hwan

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: UROLOGY JOURNAL Year:2019 | Volume:16 | Issue:3 Page(s): 255-259

Download Full-Text

View:

205

Download:

108

Cites:

Information Journal Paper

Title

UROLOGICAL ONCOLOGY: The Effect of Phosphodiesterase 5 Inhibitor on Biochemical Recurrence Following Radical Prostatectomy in Patients with Prostate Cancer

Author(s)

Keywords

phosphodiesterase 5 inhibitor

prostate cancer

prostatectomy

recurrence

Abstract

Purpose: Recently, controversy exists regarding the oncologic outcomes associated with the use of phosphodiesterase 5 inhibitor (PDE5i). Therefore, we attempted to verify the effect of PDE5i on biochemical recurrence (BCR) following radical prostatectomy (RP) in patients with prostate cancer (PCa). Materials and Methods: From January 2011 to May 2016, 351 patients who had undergone bilateral neurovascular bundle saving and who were confirmed as having pT2N0M0 disease were included in the present study. We divided these patients into three groups: no PDE5i use, PDE5i use on demand, and PDE5i use for rehabilitation. We retrospectively analyzed the effect of PDE5i on BCR of PCa. Mean follow-up period was 34. 4 months and mesurement of outcome was whether the patients developed BCR during regular follow-up. Results: 25 (7. 1%) patients showed BCR and univariate analysis found no significant differences in BCR between the three groups (5 (6. 9%) in no PDE5i use, 8 (9. 5%) in PDE5i use on demand, 12 (6. 2%) in PDE5i use for rehabilitation). Multivariable analyses showed that treatment type was not a significant factor for BCR between the groups with no PDE5i use and PDE5i use (HR = 1. 34 [0. 49– 3. 70]; P =. 573) and between the groups with on demand and rehabilitation use (HR = 1. 37 [0. 35– 5. 37]; P =. 646). Kaplan-Meier survival curves show that there were no significant differences in PSA recurrence-free survival in three groups (P >. 05). Conclusion: Use of PDE5is was not associated with any adverse effects on BCR after RP in patients with PCa.

Cites

No record.

References

CANCER STATISTICS IN KOREA: INCIDENCE, MORTALITY, SURVIVAL, AND PREVALENCE IN 2011

Cite

APA: Copy

Chung, Jae Wook, Kim, Jin Woo, Ha, Yun Sok, Choi, Seock Hwan, Lee, Jun Nyung, Kim, Bum Soo, Kim, Hyun Tae, Yoo, Eun Sang, Kwon, Tae Gyun, & Kim, Tae Hwan. (2019). UROLOGICAL ONCOLOGY: The Effect of Phosphodiesterase 5 Inhibitor on Biochemical Recurrence Following Radical Prostatectomy in Patients with Prostate Cancer. UROLOGY JOURNAL, 16(3), 255-259. SID. https://sid.ir/paper/271557/en

Vancouver: Copy

Chung Jae Wook, Kim Jin Woo, Ha Yun Sok, Choi Seock Hwan, Lee Jun Nyung, Kim Bum Soo, Kim Hyun Tae, Yoo Eun Sang, Kwon Tae Gyun, Kim Tae Hwan. UROLOGICAL ONCOLOGY: The Effect of Phosphodiesterase 5 Inhibitor on Biochemical Recurrence Following Radical Prostatectomy in Patients with Prostate Cancer. UROLOGY JOURNAL[Internet]. 2019;16(3):255-259. Available from: https://sid.ir/paper/271557/en

IEEE: Copy

Jae Wook Chung, Jin Woo Kim, Yun Sok Ha, Seock Hwan Choi, Jun Nyung Lee, Bum Soo Kim, Hyun Tae Kim, Eun Sang Yoo, Tae Gyun Kwon, and Tae Hwan Kim, “UROLOGICAL ONCOLOGY: The Effect of Phosphodiesterase 5 Inhibitor on Biochemical Recurrence Following Radical Prostatectomy in Patients with Prostate Cancer,” UROLOGY JOURNAL, vol. 16, no. 3, pp. 255–259, 2019, [Online]. Available: https://sid.ir/paper/271557/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops