EFFECT OF WILD PISTACHIO OIL ON SERUM LEPTIN CONCENTRATION AND THYROID HORMONES IN THE MALE RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SAEB MAHDI; NAZIFI S.; BEYZAEI A.; GHEYSARI REZA; JALALI JAFAR

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Endocrinology & Metabolism Year:2008 | Volume:9 | Issue:4 (SN 36) Page(s): 429-437

Download Full-Text

Persian Verion

View:

2,789

Download:

Cites:

Information Journal Paper

Title

EFFECT OF WILD PISTACHIO OIL ON SERUM LEPTIN CONCENTRATION AND THYROID HORMONES IN THE MALE RAT

Author(s)

Keywords

WILD PISTACHIO OIL (PISTACIA ATLANTICA SUBSPECIES MUTICA)Q3

LEPTINQ2

THYROID HORMONESQ3

MALE RATQ2

Abstract

Introduction: Unsaturated fatty acids are known to decrease serum LEPTIN level. Considering that wild pistachio oil is a rich source of UFA and the reciprocal effects between LEPTIN and THYROID HORMONES, the aim of the present study was to investigate the impact of dietary wild pistachio oil on serum LEPTIN concentration and its relationship with THYROID HORMONES. Materials and Methods: We took 28 healthy adult MALE RATs and divided them randomly in to the four groups; group 1 a control, and the other 3 groups received a normal diet without, 5, 10 and 20% of wild pistachio oil, respectively. RIA for THYROID HORMONES assay (T3 and T4) and ELISA for LEPTIN, fT3 and fT4 measurement were used. Results: After 60 days, serum LEPTIN levels reduced with increasing wild pistachio oil concentration in the diet; in the control group with normal diet, no significant alterations were seen. This reduction also was not statistically significant in the 10% wild pistachio oil group, whereas differences between groups were significant, indicating the increasing effects of increased amounts of wild pistachio oil percent on the reduction process observed. Pearson correlation coefficients were calculated between LEPTIN and THYROID HORMONES in the different sampling times. Control group did not have any significant correlation. In group 2 (fed with 5% wild pistachio oil), LEPTIN concentration had a negative significant correlation with T4 and fT3 and a positive significant correlation with fT4 in the third stage of sampling (day 30). A positive significant correlation between LEPTIN concentration and fT4 in the fifth stage of bleeding (day 60) was observed in group 3 (fed with 10% wild pistachio oil). In group 4 (fed with 20 % wild pistachio oil) a significant negative correlation between LEPTIN concentration and fT3 was observed in the second stage of sampling (day 15). Conclusion: Wild pistachio oil has a high content of unsaturated fatty acids, and reductins in serum LEPTIN levels in the rats studied can be due to these acids. Oral consumption of wild pistachio oil has a positive effect on reductiong LEPTIN and LDLcholesterol THYROID HORMONES and prevention of cardiovascular diseases.

Cites

References

Cite

APA: Copy

SAEB, MAHDI, NAZIFI, S., BEYZAEI, A., GHEYSARI, REZA, & JALALI, JAFAR. (2008). EFFECT OF WILD PISTACHIO OIL ON SERUM LEPTIN CONCENTRATION AND THYROID HORMONES IN THE MALE RAT. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 9(4 (SN 36)), 429-437. SID. https://sid.ir/paper/27162/en

Vancouver: Copy

SAEB MAHDI, NAZIFI S., BEYZAEI A., GHEYSARI REZA, JALALI JAFAR. EFFECT OF WILD PISTACHIO OIL ON SERUM LEPTIN CONCENTRATION AND THYROID HORMONES IN THE MALE RAT. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2008;9(4 (SN 36)):429-437. Available from: https://sid.ir/paper/27162/en

IEEE: Copy

MAHDI SAEB, S. NAZIFI, A. BEYZAEI, REZA GHEYSARI, and JAFAR JALALI, “EFFECT OF WILD PISTACHIO OIL ON SERUM LEPTIN CONCENTRATION AND THYROID HORMONES IN THE MALE RAT,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 9, no. 4 (SN 36), pp. 429–437, 2008, [Online]. Available: https://sid.ir/paper/27162/en

Related Journal Papers