ROLE OF SOY PROTEIN ON BONE TURNOVER

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HAGHIGHIAN ROUDSARI A.; MAGHBOULI ZH.; TAHBAZ F.; ARDESHIR LARIJANI MOHAMMAD BAGHER; KIMIAGAR SEYED MASOUD

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Paper Information

Journal: Iranian Journal of Public Health Year:2004 | Volume:33 | Issue:A SUPPLEMENTARY ISSUE ON OSTEOPOROSIS Page(s): 43-48

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Title

ROLE OF SOY PROTEIN ON BONE TURNOVER

Author(s)

Keywords

SOY PROTEIN

ISOFLAVONES

POSTMENOPAUS

BONE TURNOVER

Abstract

Bone mass loss is one of the commonest menopause symptoms, resulting from cessation of estrogen production. Compounds which have estrogen – like biological activity similar to "Isoflavones" present in plants especially soy, may reduce bone loss in POSTMENOPAUSal women, because as they are similar in structure to estrogens. This study, therefore, was undertaken to assess the effect of SOY PROTEIN on bone metabolism biomarkers in POSTMENOPAUSal women with osteopenia. This "before and after" clinical trial was carried out, on 15 POSTMENOPAUSal women with osteopenia, between 45 to 64 years of age. The subjects were asked to consume 35 gram/day of SOY PROTEIN for 12 weeks. Blood and urine samples, were taken at 0, 6 and 12 weeks of the study. Anthropometric measurements and a 2-day dietary recall were done at the beginning of the study, and at the 6 and 12 weeks. The food consumption data were analyzed by "Food Proccessor" software. Repeated measurement analysis was utilized to det ermine the changes in biochemical indices, anthropometric and dietary data. P-values less than 0.05 were considered as significant. Comparison of weight, BMI, physical activity and dietary intake of subjects during the study did not show any significant differences. SOY PROTEIN consumption, showed significant reductions in deoxypyridinoline (biochemical marker of bone resorption) and significant increase in total alkaline phosphatase ( biochemical marker of bone formation). There were no significant differences in serum osteocalcin, C- telopeptide, insulin- like growth factor binding protein 3 (IGFBP3), and type-I- collagen telopeptides. Considering the beneficial effects of SOY PROTEIN consumption on bone metabolism biomarkers, inclusion of this inexpensive and available food item in POSTMENOPAUSal women diet, may reduce bone loss and could be recommended for the prevention of osteoporosis.

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APA: Copy

HAGHIGHIAN ROUDSARI, A., MAGHBOULI, ZH., TAHBAZ, F., ARDESHIR LARIJANI, MOHAMMAD BAGHER, & KIMIAGAR, SEYED MASOUD. (2004). ROLE OF SOY PROTEIN ON BONE TURNOVER. IRANIAN JOURNAL OF PUBLIC HEALTH, 33(A SUPPLEMENTARY ISSUE ON OSTEOPOROSIS), 43-48. SID. https://sid.ir/paper/272651/en

Vancouver: Copy

HAGHIGHIAN ROUDSARI A., MAGHBOULI ZH., TAHBAZ F., ARDESHIR LARIJANI MOHAMMAD BAGHER, KIMIAGAR SEYED MASOUD. ROLE OF SOY PROTEIN ON BONE TURNOVER. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2004;33(A SUPPLEMENTARY ISSUE ON OSTEOPOROSIS):43-48. Available from: https://sid.ir/paper/272651/en

IEEE: Copy

A. HAGHIGHIAN ROUDSARI, ZH. MAGHBOULI, F. TAHBAZ, MOHAMMAD BAGHER ARDESHIR LARIJANI, and SEYED MASOUD KIMIAGAR, “ROLE OF SOY PROTEIN ON BONE TURNOVER,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 33, no. A SUPPLEMENTARY ISSUE ON OSTEOPOROSIS, pp. 43–48, 2004, [Online]. Available: https://sid.ir/paper/272651/en

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