OCCURENCE OF PERMANENT HYPOTHYROIDISM IN PATIENTS WITH POSTPARTUM THYROIDITIS

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SHAHBAZIAN HAJIEH; KHODADADI MAHDI; SHIRZADI R.

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Journal: IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM) Year:2010 | Volume:11 | Issue:6 (SN 48) Page(s): 680-685

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Title

OCCURENCE OF PERMANENT HYPOTHYROIDISM IN PATIENTS WITH POSTPARTUM THYROIDITIS

Author(s)

SHAHBAZIAN HAJIEH | KHODADADI MAHDI | SHIRZADI R. | Issue Writer Certificate

Keywords

PERMANENT HYPOTHYROIDISMQ3

POSTPARTUM THYROIDITISQ3

T4Q3

TSHQ3

Abstract

Introduction: POSTPARTUM THYROIDITIS is often a syndrome of transient thyroid dysfunction, but can develop to PERMANENT HYPOTHYROIDISM in some patients. The incidence of POSTPARTUM THYROIDITIS is variably reported, ranging from 1.1% to 16.7%, with an incidence ranging between 11% to 63% for PERMANENT HYPOTHYROIDISM. This study was conducted to assess the prevalence of PERMANENT HYPOTHYROIDISM after POSTPARTUM THYROIDITIS in Ahwaz.Materials and Methods: All cases of POSTPARTUM THYROIDITIS referred to the endocrinology clinic between 1999 March and 2007 March were followed for 2 to 10 years. Levothyroxin was administered for 6 to 24 months after diagnosis, and then discontinued to evaluate the patients. Based on laboratory hormonal tests, patients were divided into 3 groups: 1) Normal thyroid function test, 2) Sub clinical hypothyroidism, and 3) Clinical hypothyroidism.Results: Fifty-eight women, were followed 6 months after discontinuing levothyroxin, twenty five (43.1%) of group 1, 13 (22.4%) of group 2, and 20 (34.5%) in group 3. The average T4 level was significantly higher in group 1 compared to groups 2 and 3 (p=0.003).PERMANENT HYPOTHYROIDISM was more frequent in patients who initially (during POSTPARTUM THYROIDITIS) had TSH levels >10 mg/dL. Occurrence of PERMANENT HYPOTHYROIDISM was less frequent in patients who were initially hyperthyroid. (p=0.006)Conclusion: It is concluded that a high percentage of patients with POSTPARTUM THYROIDITIS proceed to permanent thyroid failure. The timely recognition of mild to severe cases of POSTPARTUM THYROIDITIS is important for the improvement of life for mothers and infants.

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APA: Copy

SHAHBAZIAN, HAJIEH, KHODADADI, MAHDI, & SHIRZADI, R.. (2010). OCCURENCE OF PERMANENT HYPOTHYROIDISM IN PATIENTS WITH POSTPARTUM THYROIDITIS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 11(6 (SN 48)), 680-685. SID. https://sid.ir/paper/27358/en

Vancouver: Copy

SHAHBAZIAN HAJIEH, KHODADADI MAHDI, SHIRZADI R.. OCCURENCE OF PERMANENT HYPOTHYROIDISM IN PATIENTS WITH POSTPARTUM THYROIDITIS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2010;11(6 (SN 48)):680-685. Available from: https://sid.ir/paper/27358/en

IEEE: Copy

HAJIEH SHAHBAZIAN, MAHDI KHODADADI, and R. SHIRZADI, “OCCURENCE OF PERMANENT HYPOTHYROIDISM IN PATIENTS WITH POSTPARTUM THYROIDITIS,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 11, no. 6 (SN 48), pp. 680–685, 2010, [Online]. Available: https://sid.ir/paper/27358/en

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