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Information Journal Paper

Title

MULTIPLE SCLEROSIS ASSOCIATED RISK FACTORS: A CASE-CONTROL STUDY

Pages

  1498-1505

Abstract

 Background: Hamadan Province is one of the high-risk regions in IRAN for MULTIPLE SCLEROSIS (MS). A majority of the epidemiological studies conducted in IRAN addressing MS are descriptive. This study was conducted to assess MS and its associated RISK FACTORS in Hamadan Province, the west of IRAN.Methods: This CASE-CONTROL STUDY compared 100 patients with MS (case group) and 100 patients with acute infectious diseases (control group) from September 2013 to March 2014. A checklist was used to assess the demographic, medi-cal, and family history of the patients. The Friedman-Rosenman questionnaire was also used to assess personality type. Statistical analysis was performed using logistic regression model with Stata 11 software program.Results: The adjusted odds ratio (OR) estimate of MS was 4.37 (95% CI: 2.33, 8.20) for females compared to males; 0.15 (95% CI: 0.06, 0.43) for people aged above 50 years compared to aged 14 to 29 years; 0.44 (95% CI: 0.21, 0.91) for overweight or obese people compared to normal weights. Crude OR indicated a significant association between the occurrence of MS and exclusive breast feeding, season of birth, and smoking. However, the association was not statistically significant after adjustment for other covariates.Conclusion: The risk of MS is significantly lower in male gender, obese/overweight, and old people. Furthermore, non-smoking, non-exclusive breast-feeding, and born in autumn may increase the risk of MS but need further investi-gation. However, long-term large prospective cohort studies are needed to investigate the true effect of the potential RISK FACTORS on MS.

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    Cite

    APA: Copy

    POOROLAJAL, JALAL, MAZDEH, MEHRDOKHT, SAATCHI, MOHAMMAD, TALEBI GHANE, ELAHEH, BIDERAFSH, AZAM, LOTFI, BAHAR, FERYADRES, MOHAMMAD, & PAJOHI, KHABAT. (2015). MULTIPLE SCLEROSIS ASSOCIATED RISK FACTORS: A CASE-CONTROL STUDY. IRANIAN JOURNAL OF PUBLIC HEALTH, 44(11), 1498-1505. SID. https://sid.ir/paper/273800/en

    Vancouver: Copy

    POOROLAJAL JALAL, MAZDEH MEHRDOKHT, SAATCHI MOHAMMAD, TALEBI GHANE ELAHEH, BIDERAFSH AZAM, LOTFI BAHAR, FERYADRES MOHAMMAD, PAJOHI KHABAT. MULTIPLE SCLEROSIS ASSOCIATED RISK FACTORS: A CASE-CONTROL STUDY. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2015;44(11):1498-1505. Available from: https://sid.ir/paper/273800/en

    IEEE: Copy

    JALAL POOROLAJAL, MEHRDOKHT MAZDEH, MOHAMMAD SAATCHI, ELAHEH TALEBI GHANE, AZAM BIDERAFSH, BAHAR LOTFI, MOHAMMAD FERYADRES, and KHABAT PAJOHI, “MULTIPLE SCLEROSIS ASSOCIATED RISK FACTORS: A CASE-CONTROL STUDY,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 44, no. 11, pp. 1498–1505, 2015, [Online]. Available: https://sid.ir/paper/273800/en

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