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Title

EFFECT OF OMEGA-3 SUPPLEMENTATION ON LIPOCALIN 2 AND RETINOL-BINDING PROTEIN 4 IN TYPE 2 DIABETIC PATIENTS

Pages

  63-69

Abstract

 Background: Serum levels of LIPOCALIN 2 (LCN 2) and RETINOL-BINDING PROTEIN-4 (RBP 4), increase in type 2 DIABETES MELLITUS (T2DM). We sought to determine whether serum LCN 2 and RBP 4 change after an intervention with OMEGA-3 FATTY ACIDs supplementation in diabetic patients.Methods: Forty-five type 2 diabetic patients from Iranian Diabetic Association in Tehran, Iran in 2013 were randomly recruited into two groups: one group received 4 g/d omega-3 for 10 wk; and the control group received placebo. Blood samples, food intake records, anthropometric measurements were obtained from all participants at the begin-ning and end of the study.Results: Fasting RBP 4 plasma levels significantly changed after 10 wk supplementation (P=0.01). The LCN 2 con-centrations decreased in omega-3 group, but the changes were not statistically significant. Omega-3 supplementation had no noticeable effect on anthropometric factors.Conclusions: These findings provide a rationale for omega-3 supplements aimed at lowering serum RBP 4 levels in T2DM.

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    APA: Copy

    FARAHBAKHSH FARSI, PAYAM, DJAZAYERY, ABOLGHASSEM, ESHRAGHIAN, MOHAMMAD REZA, KOOHDANI, FARIBA, ZAREI, MAHNAZ, JAVANBAKHT, MOHAMMAD HASSAN, DERAKHSHANIAN, HODA, & DJALALI, MAHMOUD. (2016). EFFECT OF OMEGA-3 SUPPLEMENTATION ON LIPOCALIN 2 AND RETINOL-BINDING PROTEIN 4 IN TYPE 2 DIABETIC PATIENTS. IRANIAN JOURNAL OF PUBLIC HEALTH, 45(1), 63-69. SID. https://sid.ir/paper/273960/en

    Vancouver: Copy

    FARAHBAKHSH FARSI PAYAM, DJAZAYERY ABOLGHASSEM, ESHRAGHIAN MOHAMMAD REZA, KOOHDANI FARIBA, ZAREI MAHNAZ, JAVANBAKHT MOHAMMAD HASSAN, DERAKHSHANIAN HODA, DJALALI MAHMOUD. EFFECT OF OMEGA-3 SUPPLEMENTATION ON LIPOCALIN 2 AND RETINOL-BINDING PROTEIN 4 IN TYPE 2 DIABETIC PATIENTS. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2016;45(1):63-69. Available from: https://sid.ir/paper/273960/en

    IEEE: Copy

    PAYAM FARAHBAKHSH FARSI, ABOLGHASSEM DJAZAYERY, MOHAMMAD REZA ESHRAGHIAN, FARIBA KOOHDANI, MAHNAZ ZAREI, MOHAMMAD HASSAN JAVANBAKHT, HODA DERAKHSHANIAN, and MAHMOUD DJALALI, “EFFECT OF OMEGA-3 SUPPLEMENTATION ON LIPOCALIN 2 AND RETINOL-BINDING PROTEIN 4 IN TYPE 2 DIABETIC PATIENTS,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 45, no. 1, pp. 63–69, 2016, [Online]. Available: https://sid.ir/paper/273960/en

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