EFFECT OF AQUEOUS EXTRACT OF OLIVE LEAF ON SERUM GLUCOSE AND LIPIDS IN DIABETIC RATS

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KOMEYLI GH.R.; MIRI MOGHADAM E.

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Paper Information

Journal: IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM) Year:2008 | Volume:10 | Issue:4 (SN 40) Page(s): 389-394

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Title

EFFECT OF AQUEOUS EXTRACT OF OLIVE LEAF ON SERUM GLUCOSE AND LIPIDS IN DIABETIC RATS

Author(s)

KOMEYLI GH.R. | MIRI MOGHADAM E. | Issue Writer Certificate

Keywords

DIABETESQ3

OLIVE LEAF EXTRACTQ2

GLUCOSEQ3

LIPIDQ3

RATQ2

Abstract

Introduction: DIABETES mellitus is a disease that affects 6.6% of the population, approximately 3 million people, in Iran; for many years, the usage of therapeutic herbal medicine has been common in Iran. In the present study, the effects of an olive leaf liquid extract on blood levels of GLUCOSE and LIPIDs have been studied in a RAT model. Material and Methods: Twenty-four adult male Wistar strain RATs (200-250g) were divided randomly into three groups (experimental, diabetic and non diabetic controls), and housed in single cages. DIABETES was induced with injection of Stereptozocine (60 mg/kg, i.p.) and the control group was given an injection of normal saline. The experimental group received aqueous extract of olive leave (750 mg/kg) intra gastric for four weeks. Finally, blood samples were taken and measured for GLUCOSE and LIPIDs levels. Results: Administration of OLIVE LEAF EXTRACT caused a significant decrease in blood levels of GLUCOSE, cholesterol and triglycerides (P<0.01), whereas an increase in HDL-C levels was seen (P<0.05), with no significant changes in LDL-C values in diabetic RATs. Conclusion: It appears that olives plant extract can have significant effects on various blood GLUCOSE and LIPIDs in diabetic RATs, although further work is needed to elucidate the extent and mechanism of these changes.

Cites

EFFECT OF MORUS ALBA LEAF EXTRACT ON SERUM GLUCOSE AND LIPIDS IN DIABETIC RATS

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APA: Copy

KOMEYLI, GH.R., & MIRI MOGHADAM, E.. (2008). EFFECT OF AQUEOUS EXTRACT OF OLIVE LEAF ON SERUM GLUCOSE AND LIPIDS IN DIABETIC RATS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 10(4 (SN 40)), 389-394. SID. https://sid.ir/paper/27402/en

Vancouver: Copy

KOMEYLI GH.R., MIRI MOGHADAM E.. EFFECT OF AQUEOUS EXTRACT OF OLIVE LEAF ON SERUM GLUCOSE AND LIPIDS IN DIABETIC RATS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2008;10(4 (SN 40)):389-394. Available from: https://sid.ir/paper/27402/en

IEEE: Copy

GH.R. KOMEYLI, and E. MIRI MOGHADAM, “EFFECT OF AQUEOUS EXTRACT OF OLIVE LEAF ON SERUM GLUCOSE AND LIPIDS IN DIABETIC RATS,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 10, no. 4 (SN 40), pp. 389–394, 2008, [Online]. Available: https://sid.ir/paper/27402/en

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