POPULATION-BASED PROSTATE CANCER SCREENING IN KAZAKHSTAN

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ISHKININ YEVGENIY

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Iranian Journal of Public Health Year:2017 | Volume:46 | Issue:7 Page(s): 917-922

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Information Journal Paper

Title

POPULATION-BASED PROSTATE CANCER SCREENING IN KAZAKHSTAN

Author(s)

ISHKININ YEVGENIY | Issue Writer Certificate

Keywords

PROSTATE CANCER

PSA

PHI

POPULATION-BASED SCREENING

EARLY DIAGNOSIS

Abstract

Background: Issues of mass screening for PROSTATE CANCER rather controversial since 2013 in 11 regions of Ka-zakhstan introduced a POPULATION-BASED SCREENING for PROSTATE CANCER, so we need to evaluate its results.Methods: In different regions of Kazakhstan during 2013-2015, a total of 321548 prostate-specific antigens (PSA) were determined in men aged 50-66 yr, under the Prostate Health Index (PHI) and transrectal ultrasonography (TRUS) guided prostate biopsy with histological examination.Results: PSA level up to 4 ng/ml in 310870 (96.7%) men, PSA level between 4 and 10 ng/ml in 8 624 (2.7%) men, PSA level above 10 ng/ml in 2054 (0.6%) men. PHI was identified in 5716 (1.8%) men, of which 2867 cases were with PHI ≥ 25 (35.9%). Totally, 3680 biopsies (1.1%) of the prostate were performed. As part of the screening, 2870 cases (0.88%) of benign prostatic hyperplasia and prostatic intraepithelial neoplasia were found. Of 742 cases of PROSTATE CANCER (0.23%) were revealed. The stages of PROSTATE CANCER screening were as follows: stage I in 172 men (23.2%), stage II in 444 men (59.8%), stage III in 98 men (13.2%) and stage IV in 28 (3.8%) men. The indicators of PROSTATE CANCER EARLY DIAGNOSIS in the I-II stages were bigger in the “screening regions” than in the “traditional diagnostics” regions: RR 1.35 95% CI (1.24 – 1.46), OR 1.84 95% CI (1.58–2.15). PROSTATE CANCER was detected at I-II stages in the "screening" regions only by screening vs traditional diagnostics, with RR 1.64 95% CI (1.56 – 1.73), OR 4.77 95% CI (3.87–5.87).Conclusion: Implementation of screening can improve the diagnosis of PROSTATE CANCER in the early stages.

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APA: Copy

ISHKININ, YEVGENIY. (2017). POPULATION-BASED PROSTATE CANCER SCREENING IN KAZAKHSTAN. IRANIAN JOURNAL OF PUBLIC HEALTH, 46(7), 917-922. SID. https://sid.ir/paper/274201/en

Vancouver: Copy

ISHKININ YEVGENIY. POPULATION-BASED PROSTATE CANCER SCREENING IN KAZAKHSTAN. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2017;46(7):917-922. Available from: https://sid.ir/paper/274201/en

IEEE: Copy

YEVGENIY ISHKININ, “POPULATION-BASED PROSTATE CANCER SCREENING IN KAZAKHSTAN,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 46, no. 7, pp. 917–922, 2017, [Online]. Available: https://sid.ir/paper/274201/en

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