APPLICATION VALUES OF T-SPOT. TB IN CLINICAL RAPID DIAGNOSIS OF TUBERCULOSIS

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ZHU FENG; OU QINFANG; ZHENG JIAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Iranian Journal of Public Health Year:2018 | Volume:47 | Issue:1 Page(s): 18-33

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Title

APPLICATION VALUES OF T-SPOT. TB IN CLINICAL RAPID DIAGNOSIS OF TUBERCULOSIS

Author(s)

ZHU FENG | OU QINFANG | ZHENG JIAN | Issue Writer Certificate

Keywords

T-SPOT.TB

ANTI-TB-AB

MYCOBACTERIUM TB-DNA

Abstract

the application value of tuberculosis-specific enzyme-linked immunospot assay (T-SPOT. TB) in the diagnosis of tuberculosis. Methods: Fifty one patients with tuberculosis (TB) admitted to Wuxi No. 5 People’ s Hospital, Wuxi, China from June 2015 to June 2017 were selected as the TB group, and 40 patients without tuberculosis admitted in the same period were randomly selected as the non-TB group. Patients in the two groups received T-SPOT. TB, TB antibody (TB-Ab) test and mycobacterium TB deoxyribonucleic acid (TB-DNA) test, and the results were compared. Results: Comparisons of the sensitivity of the three methods showed that the sensitivity of T-SPOT. TB was the highest, followed by TB-DNA from sputum samples, and that of TB-Ab was the lowest. The specificity of TB-Ab was the highest, followed by T-SPOT. TB, and that of TB-DNA from sputum samples was the lowest. In the receiver operating characteristic (ROC) curve analysis, the area under curve (AUC) of T-SPOT. TB (0. 896) was the highest, followed by TB-DNA from sputum samples (0. 772), and that of sputum smears (0. 698) was the lowest. Conclusion: T-SPOT. TB can quickly and accurately determine the presence of tuberculosis infection, and it is a non-invasive examination, which can further assist in the diagnosis and guide the treatment.

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APA: Copy

ZHU, FENG, OU, QINFANG, & ZHENG, JIAN. (2018). APPLICATION VALUES OF T-SPOT. TB IN CLINICAL RAPID DIAGNOSIS OF TUBERCULOSIS. IRANIAN JOURNAL OF PUBLIC HEALTH, 47(1), 18-33. SID. https://sid.ir/paper/274732/en

Vancouver: Copy

ZHU FENG, OU QINFANG, ZHENG JIAN. APPLICATION VALUES OF T-SPOT. TB IN CLINICAL RAPID DIAGNOSIS OF TUBERCULOSIS. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2018;47(1):18-33. Available from: https://sid.ir/paper/274732/en

IEEE: Copy

FENG ZHU, QINFANG OU, and JIAN ZHENG, “APPLICATION VALUES OF T-SPOT. TB IN CLINICAL RAPID DIAGNOSIS OF TUBERCULOSIS,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 47, no. 1, pp. 18–33, 2018, [Online]. Available: https://sid.ir/paper/274732/en

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