Clinical Significance of Detection of Coagulation Indexes, Immune Factors and Inflammatory Factors in Patients with Pregnancy-Induced Hypertension Syndrome in China

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHI Fengmei; YU Aijun; YUAN Limei

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Public Health Year:2019 | Volume:48 | Issue:4 Page(s): 681-687

Download Full-Text

View:

159

Download:

126

Cites:

Information Journal Paper

Title

Clinical Significance of Detection of Coagulation Indexes, Immune Factors and Inflammatory Factors in Patients with Pregnancy-Induced Hypertension Syndrome in China

Author(s)

SHI Fengmei | YU Aijun | YUAN Limei | Issue Writer Certificate

Keywords

Coagulation index

Immune factor

Pregnancy-induced hypertension syndrome

Abstract

Background: To investigate the clinical significance of monitoring the Coagulation indexes, Immune factors and inflammatory factors in Pregnancy-induced hypertension syndrome (PIH). Methods: 90 pregnant women with PIH admitted in Weihaiwei People's Hospital of Shandong Province, China from 2016 to 2017 were collected, including 45 cases in mild-moderate group and 45 cases in severe group. Another 45 normal pregnant women at the same period were selected as control group. The immune indexes, four index signs of coagulation bloods and serum inflammatory factors in three groups of subjects were determined. Results: The levels of complement 3 (C3), complement 4 (C4), immunoglobulin A (IgA), immunoglobulin G (IgG) and immunoglobulin M (IgM) were successively increased in severe PIH group, mild-moderate PIH group and normal pregnancy group (P<0. 05). Compared with those in normal pregnancy group, the levels of PT, APTT and TT were significantly decreased and Fib levels were significantly increased in PIH groups (P<0. 05). Compared with those in normal pregnant women, the levels of TNF-α and IL-6 in pregnant women with PIH were significantly increased (P<0. 05), and the changes in severe PIH group were more obvious than those in mild-moderate group. Conclusion: Pregnant women with PIH are in a hypercoagulable state and have a higher risk of thrombus and secondary hyperfibrinolysis. Immune factors and inflammatory factors are also associated with the occurrence and development of the disease. Monitoring the changes in Coagulation indexes and levels of Immune factors and inflammatory factors provide an important reference value for clinical treatment and prevention of com-plications.

Cites

No record.

References

No record.

Cite

APA: Copy

SHI, Fengmei, YU, Aijun, & YUAN, Limei. (2019). Clinical Significance of Detection of Coagulation Indexes, Immune Factors and Inflammatory Factors in Patients with Pregnancy-Induced Hypertension Syndrome in China. IRANIAN JOURNAL OF PUBLIC HEALTH, 48(4), 681-687. SID. https://sid.ir/paper/275139/en

Vancouver: Copy

SHI Fengmei, YU Aijun, YUAN Limei. Clinical Significance of Detection of Coagulation Indexes, Immune Factors and Inflammatory Factors in Patients with Pregnancy-Induced Hypertension Syndrome in China. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2019;48(4):681-687. Available from: https://sid.ir/paper/275139/en

IEEE: Copy

Fengmei SHI, Aijun YU, and Limei YUAN, “Clinical Significance of Detection of Coagulation Indexes, Immune Factors and Inflammatory Factors in Patients with Pregnancy-Induced Hypertension Syndrome in China,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 48, no. 4, pp. 681–687, 2019, [Online]. Available: https://sid.ir/paper/275139/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops