PREVENTION OF CRYSTAL GROWTH IN ACETAMINOPHEN SUSPENSIONS BY THE USE OF POLYVINYL PYRROLIDONE AND BOVINE SERUM ALBUMIN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SAEIDI M.; DALALPOUR MOHAMMADI N.; FARID J.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: DARU Journal of Pharmaceutical Sciences Year:2003 | Volume:11 | Issue:3 Page(s): 106-114

Download Full-Text

View:

527

Download:

281

Cites:

Information Journal Paper

Title

PREVENTION OF CRYSTAL GROWTH IN ACETAMINOPHEN SUSPENSIONS BY THE USE OF POLYVINYL PYRROLIDONE AND BOVINE SERUM ALBUMIN

Author(s)

SAEIDI M. | DALALPOUR MOHAMMADI N. | FARID J. | Issue Writer Certificate

Keywords

ACETAMINOPHEN SUSPENSION

CRYSTAL GROWTH INHIBITION

POLYVINYL PYRROLIDONE

BOVINE SERUM ALBUMIN

Abstract

The ability of POLYVINYL PYRROLIDONE (PVP) and BOVINE SERUM ALBUMIN (BSA) in inhibition of the crystal growth in suspensions containing Acetaminophen as a model drug was evaluated. Fort his purpose sedimentation volume, resuspendability, cake formation, particle size distribution, volume surface diameter (dvs), and crystal growth after freeze-thaw cycling of the several suspensions were evaluated. ANOVA followed by Tukey test was used to determine significant differences (P<0.05). PVP in comparison with BSA showed a better CRYSTAL GROWTH INHIBITION and at concentrations of 50100 mg/100 ml inhibited crystal growth over 150 days. The combination of PVP and BSA showed an inhibition of acetaminophen crystal growth after 45 and 150 days respectively. The combination of PVP (50 mg/100 ml) and BSA (80 mg/100 ml) showed interesting results regarding sedimentation volume, resuspendability, prevention of cake formation, and CRYSTAL GROWTH INHIBITION; and offer new perspectives in the preparation of suspensions.

Cites

No record.

References

Cite

APA: Copy

SAEIDI, M., DALALPOUR MOHAMMADI, N., & FARID, J.. (2003). PREVENTION OF CRYSTAL GROWTH IN ACETAMINOPHEN SUSPENSIONS BY THE USE OF POLYVINYL PYRROLIDONE AND BOVINE SERUM ALBUMIN. DARU JOURNAL OF PHARMACEUTICAL SCIENCE, 11(3), 106-114. SID. https://sid.ir/paper/275177/en

Vancouver: Copy

SAEIDI M., DALALPOUR MOHAMMADI N., FARID J.. PREVENTION OF CRYSTAL GROWTH IN ACETAMINOPHEN SUSPENSIONS BY THE USE OF POLYVINYL PYRROLIDONE AND BOVINE SERUM ALBUMIN. DARU JOURNAL OF PHARMACEUTICAL SCIENCE[Internet]. 2003;11(3):106-114. Available from: https://sid.ir/paper/275177/en

IEEE: Copy

M. SAEIDI, N. DALALPOUR MOHAMMADI, and J. FARID, “PREVENTION OF CRYSTAL GROWTH IN ACETAMINOPHEN SUSPENSIONS BY THE USE OF POLYVINYL PYRROLIDONE AND BOVINE SERUM ALBUMIN,” DARU JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 11, no. 3, pp. 106–114, 2003, [Online]. Available: https://sid.ir/paper/275177/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops