مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Cites:

Information Journal Paper

Title

THE INHIBITORY EFFECT OF PROPRANOLOL AND ISOPROTERENOL ON HUMAN PLASMA CHOLINESTERASE

Pages

  158-161

Abstract

 The effect of PROPRANOLOL and ISOPROTERENOL on the hydrolysis of 4- nitrophenylbutyrate (PNPB) by the purified HUMAN PLASMA CHOLINESTERASE was studied. During the hydrolysis of PNPB, enzyme obeyed to Michaelis-Menten model. PROPRANOLOL was found to be a competitive inhibitor, and ISOPROTERENOL yielded a complex inhibition pattern. It could be explained that the inhibitory effect of PROPRANOLOL shows noncooperativity between subunits of HUMAN PLASMA CHOLINESTERASE upon binding of PNPB. In contrast, isoproternol inhibitory effects indicate more than one type of binding sites on this enzyme.

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    Cite

    APA: Copy

    AWSAT MELLATI, A., & TAJKEY, J.. (2002). THE INHIBITORY EFFECT OF PROPRANOLOL AND ISOPROTERENOL ON HUMAN PLASMA CHOLINESTERASE. DARU JOURNAL OF PHARMACEUTICAL SCIENCE, 10(4), 158-161. SID. https://sid.ir/paper/275266/en

    Vancouver: Copy

    AWSAT MELLATI A., TAJKEY J.. THE INHIBITORY EFFECT OF PROPRANOLOL AND ISOPROTERENOL ON HUMAN PLASMA CHOLINESTERASE. DARU JOURNAL OF PHARMACEUTICAL SCIENCE[Internet]. 2002;10(4):158-161. Available from: https://sid.ir/paper/275266/en

    IEEE: Copy

    A. AWSAT MELLATI, and J. TAJKEY, “THE INHIBITORY EFFECT OF PROPRANOLOL AND ISOPROTERENOL ON HUMAN PLASMA CHOLINESTERASE,” DARU JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 10, no. 4, pp. 158–161, 2002, [Online]. Available: https://sid.ir/paper/275266/en

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