PHASE DIAGRAMS OF LECITHIN-BASED MICROEMULSIONS CONTAINING SODIUM SALICYLATE

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ABOU FAZELI R.; MORTAZAVI S.A.R.; KHOSHNEVIS P.

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Journal Paper

Paper Information

Journal: DARU Journal of Pharmaceutical Sciences Year:2000 | Volume:8 | Issue:3-4 Page(s): 1-7

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Title

PHASE DIAGRAMS OF LECITHIN-BASED MICROEMULSIONS CONTAINING SODIUM SALICYLATE

Author(s)

ABOU FAZELI R. | MORTAZAVI S.A.R. | KHOSHNEVIS P. | Issue Writer Certificate

Keywords

MICROEMULSION

CO-SURFACTANT

PARTIAL PHASE DIAGRAM

SOYBEAN LECITHIN

SODIUM SALICYLATE

PHASE BEHAVIOR

Abstract

Partial phase diagrams were constructed at 25°C to investigate the phase behaviour of systems composed of SOYBEAN LECITHIN, water, SODIUM SALICYLATE, alcohol and isopropyl myristate. The lecithins used were the commercially available soy bean lecithins, namely E200 and E170 (phosphatidyl choline purities greater than 95% and 68-72% respectively). The cosurfactants employed were n-propanol, 2-propanol and n-butanol and these were used at lecithin/alcohol weight ratios (Km) of 1:1 and 1.5:1. At a given Km, the aqueous phase consisted of a 2% w/w SODIUM SALICYLATE solution. Phase diagrams showed the area of existence of a stable isotropic region along the surfactant/oil axis (i.e., reverse MICROEMULSION area). The extension of the MICROEMULSION domain was influenced by the purity of surfactant, the lecithin/alcohol weight ratios and the kind of the alcohol.

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APA: Copy

ABOU FAZELI, R., MORTAZAVI, S.A.R., & KHOSHNEVIS , P.. (2000). PHASE DIAGRAMS OF LECITHIN-BASED MICROEMULSIONS CONTAINING SODIUM SALICYLATE. DARU JOURNAL OF PHARMACEUTICAL SCIENCE, 8(3-4), 1-7. SID. https://sid.ir/paper/275301/en

Vancouver: Copy

ABOU FAZELI R., MORTAZAVI S.A.R., KHOSHNEVIS P.. PHASE DIAGRAMS OF LECITHIN-BASED MICROEMULSIONS CONTAINING SODIUM SALICYLATE. DARU JOURNAL OF PHARMACEUTICAL SCIENCE[Internet]. 2000;8(3-4):1-7. Available from: https://sid.ir/paper/275301/en

IEEE: Copy

R. ABOU FAZELI, S.A.R. MORTAZAVI, and P. KHOSHNEVIS , “PHASE DIAGRAMS OF LECITHIN-BASED MICROEMULSIONS CONTAINING SODIUM SALICYLATE,” DARU JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 8, no. 3-4, pp. 1–7, 2000, [Online]. Available: https://sid.ir/paper/275301/en

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