Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

790
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

543
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

1

Information Journal Paper

Title

IN VITRO ANTIOXIDANT PROPERTY OF THE EXTRACT OF EXCOECARIA AGALLOCHA (EUPHORBIACEAE)

Pages

  149-154

Abstract

 Background and objectives: EXCOECARIA AGALLOCHA L. (Family: EUPHORBIACEAE) is a Bangladeshi medicinal plant found predominantly in the tidal forests and swamps of the Sundarbans and other coastal areas in Bangladesh. As part of our on-going phytochemical and bioactivity studies on medicinal plants from Bangladeshi flora, the in vitro ANTIOXIDANT property on the bark of this plant was evaluated. Methods: The hydroalcohol extract of the dried and ground bark of E. agallocha was assessed for ANTIOXIDANT activity using a series of well-established assays including the 2,2- diphenyl-1-picrylhydrazyl (DPPH), the lipid peroxidation by thiobarbituric acid (TBA), the reducing power, the nitric oxide (NO.) and the hydrogen peroxide (H2O2) scavenging assays. Results: In the DPPH, the NO and the H2O2 scavenging assays, the extract of E. agallocha displayed significant ANTIOXIDANT activities with the IC50 values of 179.16, 120.24 and 134.29 mg/ml, respectively. The reducing power of the extract increased dose-dependently, and the extract reduced the most Fe3+ ions to the extent less than butylated hydroxy toluene (BHT). In the lipid peroxidation assay, the extract showed significant inhibition of peroxidation effect at all concentrations, with an IC50 value of 189.27 mg/ml.Conclusion: Since REACTIVE OXYGEN SPECIES are important contributors to serious ailments such as atherosclerosis, alcoholic liver cirrhosis and cancer, the ANTIOXIDANT property of the extract of E. agallocha as observed in the present study might be useful for the development of newer and more potent ANTIOXIDANTs.

Cites

References

  • No record.

    • Cite

    APA: Copy

    SUBHAN, N., ASHRAFUL ALAM, MD., AHMED, F., ABDUL AWAL, MD., NAHAR, L., & SARKER, S.D.. (2008). IN VITRO ANTIOXIDANT PROPERTY OF THE EXTRACT OF EXCOECARIA AGALLOCHA (EUPHORBIACEAE). DARU JOURNAL OF PHARMACEUTICAL SCIENCE, 16(3), 149-154. SID. https://sid.ir/paper/275468/en

    Vancouver: Copy

    SUBHAN N., ASHRAFUL ALAM MD., AHMED F., ABDUL AWAL MD., NAHAR L., SARKER S.D.. IN VITRO ANTIOXIDANT PROPERTY OF THE EXTRACT OF EXCOECARIA AGALLOCHA (EUPHORBIACEAE). DARU JOURNAL OF PHARMACEUTICAL SCIENCE[Internet]. 2008;16(3):149-154. Available from: https://sid.ir/paper/275468/en

    IEEE: Copy

    N. SUBHAN, MD. ASHRAFUL ALAM, F. AHMED, MD. ABDUL AWAL, L. NAHAR, and S.D. SARKER, “IN VITRO ANTIOXIDANT PROPERTY OF THE EXTRACT OF EXCOECARIA AGALLOCHA (EUPHORBIACEAE),” DARU JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 16, no. 3, pp. 149–154, 2008, [Online]. Available: https://sid.ir/paper/275468/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top