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1

Information Journal Paper

Title

ASSESSMENT OF A LOW DOSE OF IV MIDAZOLAM USED ORALLY FOR CONSCIOUS SEDATION IN PEDIATRIC DENTISTRY

Pages

  79-82

Abstract

 Background and the purpose of the study: Midazolam is preferably used in pediatric dentistry for quick onset of action and recovery. The aim of this prospective, observer-blind and placebo-controlled study was to assess the efficacy of a low dose of ORAL MIDAZOLAM in modification of the behavior of young pediatric dental patients.Methods: Forty children aged 3 to 5 years who displayed ratings 1 or 2 on the Frankl Scale and were healthy by the American Society of Anesthesiologists-I status were randomly divided into two experimental and control groups of 20 each. All children required pulpotomy and restoration of D and E teeth and received either 0.25mg/kg of a 15mg/3ml IV midazolam mixed in black cherry syrup or the syrup alone. Subjects were continuously observed and monitored with pulse oximetry. Houpt's Behavioral Ratings was used to determine the overall behavior, the degree of crying and movement during treatment. Mann-Whitney U test was used for statistical analysis.Results and major conclusion: Patients who received 0.25mg/kg of the prepared ORAL MIDAZOLAM significantly behaved better during treatment than the placebo controls (P<0.05). In comparison with the placebo group, reduced movement and crying were observed in the midazolam group (P<0.05). No adverse effects were observed and treatments were completed successfully. A low dose of 0.25mg/kg of a 15mg/3ml IV midazolam mixed in black cherry syrup was found to be effective in CONSCIOUS SEDATION of young pediatric dental patients.

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    APA: Copy

    MORTAZAVI, M., POURHASHEMI, S.J., KHOSRAVI, M.B., ASHTARI, S., & GHADERI, F.. (2009). ASSESSMENT OF A LOW DOSE OF IV MIDAZOLAM USED ORALLY FOR CONSCIOUS SEDATION IN PEDIATRIC DENTISTRY. DARU JOURNAL OF PHARMACEUTICAL SCIENCE, 17(2), 79-82. SID. https://sid.ir/paper/275501/en

    Vancouver: Copy

    MORTAZAVI M., POURHASHEMI S.J., KHOSRAVI M.B., ASHTARI S., GHADERI F.. ASSESSMENT OF A LOW DOSE OF IV MIDAZOLAM USED ORALLY FOR CONSCIOUS SEDATION IN PEDIATRIC DENTISTRY. DARU JOURNAL OF PHARMACEUTICAL SCIENCE[Internet]. 2009;17(2):79-82. Available from: https://sid.ir/paper/275501/en

    IEEE: Copy

    M. MORTAZAVI, S.J. POURHASHEMI, M.B. KHOSRAVI, S. ASHTARI, and F. GHADERI, “ASSESSMENT OF A LOW DOSE OF IV MIDAZOLAM USED ORALLY FOR CONSCIOUS SEDATION IN PEDIATRIC DENTISTRY,” DARU JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 17, no. 2, pp. 79–82, 2009, [Online]. Available: https://sid.ir/paper/275501/en

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