مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF THE EXTRACT AND ESSENTIAL OIL OF ROSA DAMASCENA FROM IRAN, POPULATION OF GUILAN

Pages

  175-180

Abstract

 Background and the purpose of study: ROSA DAMASCENA Mill. (Rosaceae) has cooling, soothing, astringent, and anti-inflammatory effects, and has been used in the north of Iran as a cardiotonic agent. The aim of this study was to identify components of R. damascena (cultivated in Guilan Province) extract and ESSENTIAL OIL and to study their biological activities.Methods: ESSENTIAL OIL of R. damascena was prepared by hydrodistillation and analyzed with GC/MS instrument. The ANTIOXIDANT activity of hydro-alcohlic extract of petals and ESSENTIAL OIL was measured using free radical scavenging activity with 2-2-diphenyl, 1-picrylhydrazyl (DPPH) and lipid peroxidation (ferric ammonium thiocyanate) methods.Results: Hydro-alcoholic extract showed strong free radical scavenging capacity compared to lipid peroxidation inhibitory effects. IC50 values of the extract were 2.24 mg/mL and 520 mg/mL in free radical scavenging and lipid peroxidation assays, respectively. The major components of ESSENTIAL OIL were linalool (3.8%), nerol (3.05%), geraniol (15.05%), 1-nonadecene (18.56%), n-tricosane (16.68%), hexatriacontane (24.6%) and n-pentacosane (3.37%). The bioassay-guided fractionation of extract led to the isolation of three flavonol glycosides: quercetin-3-O-glucoside, kaempferol-3-O-rhamnoside and kaempferol-3-O-arabinoside. The IC 50 value of the radical scavenging activity of kaempferol-3-O-rhamnoside which was, 530 mg/mL was weaker than the extract.Major conclusion: The petal of this cultivated rose has no bitter taste and because of its potential ANTIOXIDANT activity and good taste, can be used as food flavor and a preventing agent for many diseases.

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    • Cite

    APA: Copy

    YASA, N., MASOUMI, F., ROUHANI RANKOUHI, S.E., & HAJI AKHOUNDI, A.. (2009). CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF THE EXTRACT AND ESSENTIAL OIL OF ROSA DAMASCENA FROM IRAN, POPULATION OF GUILAN. DARU JOURNAL OF PHARMACEUTICAL SCIENCE, 17(3), 175-180. SID. https://sid.ir/paper/275513/en

    Vancouver: Copy

    YASA N., MASOUMI F., ROUHANI RANKOUHI S.E., HAJI AKHOUNDI A.. CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF THE EXTRACT AND ESSENTIAL OIL OF ROSA DAMASCENA FROM IRAN, POPULATION OF GUILAN. DARU JOURNAL OF PHARMACEUTICAL SCIENCE[Internet]. 2009;17(3):175-180. Available from: https://sid.ir/paper/275513/en

    IEEE: Copy

    N. YASA, F. MASOUMI, S.E. ROUHANI RANKOUHI, and A. HAJI AKHOUNDI, “CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF THE EXTRACT AND ESSENTIAL OIL OF ROSA DAMASCENA FROM IRAN, POPULATION OF GUILAN,” DARU JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 17, no. 3, pp. 175–180, 2009, [Online]. Available: https://sid.ir/paper/275513/en

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