INTRODUCTION OF A MATHEMATICAL MODEL FOR OPTIMIZING THE DRUG RELEASE IN THE PATIENT’S BODY

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NABATCHIAN MOHAMMAD REZA; SHAHRIARI HAMID; SHAHRIARI MONA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: DARU Journal of Pharmaceutical Sciences Year:2014 | Volume:22 | Issue:1 Page(s): 1-12

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Title

INTRODUCTION OF A MATHEMATICAL MODEL FOR OPTIMIZING THE DRUG RELEASE IN THE PATIENT’S BODY

Author(s)

NABATCHIAN MOHAMMAD REZA | SHAHRIARI HAMID | SHAHRIARI MONA | Issue Writer Certificate

Keywords

DRUG RELEASE

TIME-ORIENTED QUALITY CHARACTERISTIC

PARAMETER DESIGN

DESIRABILITY FUNCTION

RELEASE PROFILE

Abstract

Background: DRUG RELEASE in a patient’s body is of particular interest to the pharmaceutical industry. One of the most essential types of DRUG RELEASE is the gradual release based on a behavior, which is called a profile or modified release. The investigation of the TIME-ORIENTED QUALITY CHARACTERISTIC is one of the newest topics in the area of product design. There are already several approaches addressing this issue. In this paper, a mathematical model is proposed to find the suitable values of the controllable factors in a drug to achieve the profile of the DRUG RELEASE in the patient’s body.Results: The proposed method has several advantages over the existing methods.Conclusion: The authors feel that by adjusting the control factors during the production process the DRUG RELEASE profile become closer to the reference profile.

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APA: Copy

NABATCHIAN, MOHAMMAD REZA, SHAHRIARI, HAMID, & SHAHRIARI, MONA. (2014). INTRODUCTION OF A MATHEMATICAL MODEL FOR OPTIMIZING THE DRUG RELEASE IN THE PATIENT’S BODY. DARU JOURNAL OF PHARMACEUTICAL SCIENCE, 22(1), 1-12. SID. https://sid.ir/paper/275733/en

Vancouver: Copy

NABATCHIAN MOHAMMAD REZA, SHAHRIARI HAMID, SHAHRIARI MONA. INTRODUCTION OF A MATHEMATICAL MODEL FOR OPTIMIZING THE DRUG RELEASE IN THE PATIENT’S BODY. DARU JOURNAL OF PHARMACEUTICAL SCIENCE[Internet]. 2014;22(1):1-12. Available from: https://sid.ir/paper/275733/en

IEEE: Copy

MOHAMMAD REZA NABATCHIAN, HAMID SHAHRIARI, and MONA SHAHRIARI, “INTRODUCTION OF A MATHEMATICAL MODEL FOR OPTIMIZING THE DRUG RELEASE IN THE PATIENT’S BODY,” DARU JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 22, no. 1, pp. 1–12, 2014, [Online]. Available: https://sid.ir/paper/275733/en

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