مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Cites:

1

Information Journal Paper

Title

NEW ASPECTS OF SACCHAROMYCES CEREVISIAE AS A NOVEL CARRIER FOR BERBERINE

Pages

  1-8

Abstract

 Background: BERBERINE was encapsulated in yeast cells of Saccharomyces cerevisiae as novel carriers to be used in different food and drug industries. The microcapsules were characterized by differential scanning calorimetry (DSC), fourier transform infra red spectroscopy (FT-IR) and fluorescence microscopy. The ENCAPSULATION factors such as plasmolysis of yeast cells which affects the % ENCAPSULATION yield were studied.Results: Fluorescence microscopy showed the yeast cells became fluorescent after ENCAPSULATION process. DSC diagram was representing of new peak for microcapsule which was not the same as BERBERINE and the empty yeast cells peaks, separately. FTIR spectrums of microcapsules and yeast cells were almost the same. The plasmolysed and non plasmolysed microcapsules were loaded with BERBERINE up to about 40.2±0.2% w/w.Conclusion: Analytical methods proved that BERBERINE was encapsulated in the yeast cells. Fluorescence microscopy and FTIR results showed the entrance of BERBERINE inside the yeasts. DSC diagram indicated the appearance of new peak which is due to the synthesis of new product. Although plasmolysis caused changes in yeast cell structure and properties, it did not enhance BERBERINE loading in the cells. The results confirmed that Saccharomyces cerevisiae could be an efficient and safe carrier for active materials.

Cites

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    • Cite

    APA: Copy

    SALARI, ROSHANAK, FAZLY BAZZAZ, BIBI SEDIGHEH, RAJABI, OMID, & KHASHYARMANESH, ZAHRA. (2013). NEW ASPECTS OF SACCHAROMYCES CEREVISIAE AS A NOVEL CARRIER FOR BERBERINE. DARU JOURNAL OF PHARMACEUTICAL SCIENCE, 21(9), 1-8. SID. https://sid.ir/paper/275742/en

    Vancouver: Copy

    SALARI ROSHANAK, FAZLY BAZZAZ BIBI SEDIGHEH, RAJABI OMID, KHASHYARMANESH ZAHRA. NEW ASPECTS OF SACCHAROMYCES CEREVISIAE AS A NOVEL CARRIER FOR BERBERINE. DARU JOURNAL OF PHARMACEUTICAL SCIENCE[Internet]. 2013;21(9):1-8. Available from: https://sid.ir/paper/275742/en

    IEEE: Copy

    ROSHANAK SALARI, BIBI SEDIGHEH FAZLY BAZZAZ, OMID RAJABI, and ZAHRA KHASHYARMANESH, “NEW ASPECTS OF SACCHAROMYCES CEREVISIAE AS A NOVEL CARRIER FOR BERBERINE,” DARU JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 21, no. 9, pp. 1–8, 2013, [Online]. Available: https://sid.ir/paper/275742/en

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