SEROLOGIC EVIDENCE OF PERTUSSIS INFECTION IN VACCINATED IRANIAN CHILDREN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SANAEI DASHTI ANAHITA; KARIMI ABD ELAH; ARJMANDI REZA; MOGHADAMI MOHSEN; KHEYRKHAH TAHEREH; SHIVA FARIDEH; GHOLINEJAD ZARI; JOLAEE HASAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS) Year:2012 | Volume:37 | Issue:4 Page(s): 260-265

Download Full-Text

View:

248

Download:

Cites:

Information Journal Paper

Title

SEROLOGIC EVIDENCE OF PERTUSSIS INFECTION IN VACCINATED IRANIAN CHILDREN

Author(s)

Keywords

PERTUSSIS

WHOOPING COUGH

PERTUSSIS VACCI

Abstract

Background: It seems that the incidence of PERTUSSIS-like illnesses is considerably increasing despite the wide coverage of immunization with the whole cell PERTUSSIS vaccine. We aimed to investigate the occurrence of PERTUSSIS in vaccinated children by measuring anti-PERTUSSIS antibodies.Methods: In this cross-sectional study, blood samples were taken from vaccinated children aged 2, 4, 6, 12, 18, and 72 months. Anti-PERTUSSIS IgG and IgA were measured by ELISA. P<0.05 was considered significant.Results: 725 children were enrolled in the study. Geometric mean titers for IgG that showed a slight decease after 2 months of age and increased distinctly in children aged 72 months. The frequency of the individuals whose IgG was above the determined cut-off (derived from mean+2SD) was observed in 1% of the 2, 4, and 6-month-old infants, 6% of the 12 and 18-month-olds and 12% of the 6-year -old children. Positive IgA titers were detected in 5, 9, 6, 23, 11, and 8% of children aged 2, 4, 6, 12, 18, and 72 months, respectively.Conclusion: Since a considerable percentage of children had high levels of anti-PERTUSSIS IgG antibodies (³2 SD), positive anti-PERTUSSIS IgA, and most importantly an increased level of anti-PERTUSSIS IgG geometric mean titer at 6 years of age, further investigations regarding the protection provided by the presently used PERTUSSIS vaccine seems necessary.

Cites

VIRULENCE FACTORS VARIATION AMONG BORDETELLA PERTUSSIS ISOLATES IN IRAN (LETTER TO THE EDITOR)

References

No record.

Cite

APA: Copy

SANAEI DASHTI, ANAHITA, KARIMI, ABD ELAH, ARJMANDI, REZA, MOGHADAMI, MOHSEN, KHEYRKHAH, TAHEREH, SHIVA, FARIDEH, GHOLINEJAD, ZARI, & JOLAEE, HASAN. (2012). SEROLOGIC EVIDENCE OF PERTUSSIS INFECTION IN VACCINATED IRANIAN CHILDREN. IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS), 37(4), 260-265. SID. https://sid.ir/paper/276467/en

Vancouver: Copy

SANAEI DASHTI ANAHITA, KARIMI ABD ELAH, ARJMANDI REZA, MOGHADAMI MOHSEN, KHEYRKHAH TAHEREH, SHIVA FARIDEH, GHOLINEJAD ZARI, JOLAEE HASAN. SEROLOGIC EVIDENCE OF PERTUSSIS INFECTION IN VACCINATED IRANIAN CHILDREN. IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS)[Internet]. 2012;37(4):260-265. Available from: https://sid.ir/paper/276467/en

IEEE: Copy

ANAHITA SANAEI DASHTI, ABD ELAH KARIMI, REZA ARJMANDI, MOHSEN MOGHADAMI, TAHEREH KHEYRKHAH, FARIDEH SHIVA, ZARI GHOLINEJAD, and HASAN JOLAEE, “SEROLOGIC EVIDENCE OF PERTUSSIS INFECTION IN VACCINATED IRANIAN CHILDREN,” IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS), vol. 37, no. 4, pp. 260–265, 2012, [Online]. Available: https://sid.ir/paper/276467/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops