BENEFICIAL EFFECTS OF VITAMIN C AND VITAMIN E ON BLOOD PRESSURE IN HYPERANDROGENIC WOMEN

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SOTOUDEH G.; SIASI F.; MIRDAMADI S.R.; MOHAMMAD K.; GOLESTAN B.; CHAMARI M.

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Journal: ACTA MEDICA IRANICA Year:2002 | Volume:40 | Issue:3 Page(s): 181-186

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Title

BENEFICIAL EFFECTS OF VITAMIN C AND VITAMIN E ON BLOOD PRESSURE IN HYPERANDROGENIC WOMEN

Author(s)

Keywords

VITAMIN C

VITAMIN E

BLOOD PRESSURE

ANDROGEN EXCESS

Abstract

Hyperandrogenism affects 2-6% of all women. Hypertension is one of disturbances which is related to ANDROGEN EXCESS. Higher intakes of VITAMIN C and VITAMIN E have been associated with lower blood pressure. Tho investigate the effect of these vitamin supplementation on BLOOD PRESSURE in hyperandrogenic women, a randomized, double-blind, placebo-controlled study was designed on 56 women 18-54 years old. Women were randomly allocated to one of four treatment groups: spironolactone plus vitamain C and viamin E (SCE), spironolactone plus vitamins placebo (SP), VITAMIN C plus VITAMIN E (CE), vitamins placebo (P). The treatment consisted of oral administration of 100 mg spironolactone, 1000 mg VITAMIN C and 900 mg VITAMIN E (alpha-tocopherol acetate) daily for about 3 months. Results indicated that compared to pretreatment, vitamins supplementation significantly lowered systolic (119.1±12.6 vs. 112.6±15.4 mmHg) and mean BLOOD PRESSURE (97.4±11.5 vs. 92. ±12.1 mmHg) SCE group (P<0.05), diastolic (87.3±12.7 vs. 80±12 mmHg) and mean group (P<0.05). Blood levels of VITAMIN C and alpha-tocopherol increased in all SCE and CE subjects. In conclusion, VITAMIN C and VITAMIN E supplementation reduced BLOOD PRESSURE in hperandrogenic women who are at risk of hypertension.

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APA: Copy

SOTOUDEH, G., SIASI, F., MIRDAMADI, S.R., MOHAMMAD, K., GOLESTAN, B., & CHAMARI, M.. (2002). BENEFICIAL EFFECTS OF VITAMIN C AND VITAMIN E ON BLOOD PRESSURE IN HYPERANDROGENIC WOMEN. ACTA MEDICA IRANICA, 40(3), 181-186. SID. https://sid.ir/paper/277723/en

Vancouver: Copy

SOTOUDEH G., SIASI F., MIRDAMADI S.R., MOHAMMAD K., GOLESTAN B., CHAMARI M.. BENEFICIAL EFFECTS OF VITAMIN C AND VITAMIN E ON BLOOD PRESSURE IN HYPERANDROGENIC WOMEN. ACTA MEDICA IRANICA[Internet]. 2002;40(3):181-186. Available from: https://sid.ir/paper/277723/en

IEEE: Copy

G. SOTOUDEH, F. SIASI, S.R. MIRDAMADI, K. MOHAMMAD, B. GOLESTAN, and M. CHAMARI, “BENEFICIAL EFFECTS OF VITAMIN C AND VITAMIN E ON BLOOD PRESSURE IN HYPERANDROGENIC WOMEN,” ACTA MEDICA IRANICA, vol. 40, no. 3, pp. 181–186, 2002, [Online]. Available: https://sid.ir/paper/277723/en

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