SELECTIVE EVALUATION OF TWO URINARY ENZYMES (NAG AND AAP) BEFORE AND AFTER UNILATERAL SHOCK WAVE LITHOTRIPSY

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NIKOUBAKHT M.R.; POURMAND G.; AMIDI A.; HASHEMI H.; ABEDI A.R.

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Journal Paper

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Journal: ACTA MEDICA IRANICA Year:2006 | Volume:44 | Issue:5 Page(s): 299-304

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Title

SELECTIVE EVALUATION OF TWO URINARY ENZYMES (NAG AND AAP) BEFORE AND AFTER UNILATERAL SHOCK WAVE LITHOTRIPSY

Author(s)

Keywords

EXTROCORPORAL SHOCK WAVE LITHOTRIPSY

ALANINE AMINOPEPTIDASE

N-ACETYL-GLUCOSAMINIDASE

URINARY ENZYMES

MORBIDITY

Abstract

We have evaluated two URINARY ENZYMES activity N-acetyl-B-D-glucosamine (NAG) and alanine amino peptidase (AAP) before and after unilateral ESWL as markers for renal parenchymal damage. Forty eight patients with kidney stones (mean age 39) who had presented for the first time or at least one year after their previous lithotripsy underwent ESWL. Urinary specimens were collected before and after first, third and seventh days of lithotripsy and NAG, AAP were evaluated. These enzymes displayed the greatest activity 24 hours after ESWL with significant difference compared to the control group, (P < 0.05 versus 0.02). Elevation of URINARY ENZYMES activity correlated with stone size particularly stones larger than 2 cm. These data suggest that there is some tubular and parenchymal damage induced by ESWL that needs time to get improved. The higher urinary enzyme activity in patients with larger stones (> 2 cm) is probably related to injury resulting from passage of smaller stones, produced after lithotripsy of a large stone, and it is suggested that these patients are treated with a safer procedure.

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APA: Copy

NIKOUBAKHT, M.R., POURMAND, G., AMIDI, A., HASHEMI, H., & ABEDI, A.R.. (2006). SELECTIVE EVALUATION OF TWO URINARY ENZYMES (NAG AND AAP) BEFORE AND AFTER UNILATERAL SHOCK WAVE LITHOTRIPSY. ACTA MEDICA IRANICA, 44(5), 299-304. SID. https://sid.ir/paper/277942/en

Vancouver: Copy

NIKOUBAKHT M.R., POURMAND G., AMIDI A., HASHEMI H., ABEDI A.R.. SELECTIVE EVALUATION OF TWO URINARY ENZYMES (NAG AND AAP) BEFORE AND AFTER UNILATERAL SHOCK WAVE LITHOTRIPSY. ACTA MEDICA IRANICA[Internet]. 2006;44(5):299-304. Available from: https://sid.ir/paper/277942/en

IEEE: Copy

M.R. NIKOUBAKHT, G. POURMAND, A. AMIDI, H. HASHEMI, and A.R. ABEDI, “SELECTIVE EVALUATION OF TWO URINARY ENZYMES (NAG AND AAP) BEFORE AND AFTER UNILATERAL SHOCK WAVE LITHOTRIPSY,” ACTA MEDICA IRANICA, vol. 44, no. 5, pp. 299–304, 2006, [Online]. Available: https://sid.ir/paper/277942/en

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