COMPARISON OF ECG ABNORMALITIES IN CHRONIC KIDNEY DISEASE AND DIABETES MELLITUS: TEHRAN LIPID AND GLUCOSE STUDY (TLGS)

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GHANBARIAN A.; SHAFIEI G.; RASHIDI ARASH; AZIZI FEREYDOUN

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Journal: IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM) Year:2005 | Volume:7 | Issue:SUPPLEMENT 4 Page(s): 449-457

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Title

COMPARISON OF ECG ABNORMALITIES IN CHRONIC KIDNEY DISEASE AND DIABETES MELLITUS: TEHRAN LIPID AND GLUCOSE STUDY (TLGS)

Author(s)

GHANBARIAN A. | SHAFIEI G. | RASHIDI ARASH | AZIZI FEREYDOUN | Issue Writer Certificate

Keywords

CKDQ4

DIABETES MELLITUSQ3

CHDQ4

Abstract

Introduction: Though ECGs have limited accuracy for determining true prevalence of coronary heart disease (CHD), we studied individulas with CKD and DM, controlled for hypertension (HTN), to determine whether their ECG abnormalities could also reflect underlying coronary heart disease. Materials & Methods: Data were collected for 5942 men and women aged 30-69 years, participants of the Tehran Lipid and Glucose Study (TLGS), a cross-sectional phase of a large epidemiological study first initiated in 1999. ECG findings of all subjects were coded according to Minnesota ECG coding criteria. The Whitehall criteria for abnormal ECG findings that could represent ischemia were utilized. GFR was estimated using the Cockroft-Gault equation and diabetes was defined according to the American Diabetic Association (ADA) criteria. Subjects with moderate CKD and without DM were compared to the patients with DM without CKD. HTN prevalence was similar. The analysis was performed for all Whitehall ECG ischemia abnormalities combined, and separately for pathologic Q waves. Results: In spite of an overall similar prevalence of smoking, and a lower incidence of dyslipidemia and HTN, moderate CKD patients had a higher prevalence of Whitehall criteria abnormal ECG findings compared to the patients with DM. 19.7% of patients with CKD had abnormal ECG findings while 14.7% of diabetes patients had abnormal ECGs (p=0.02). The prevalence of Q waves was 11.5% in patients with CKD and 10.8% in patients with DM. In an age matched sub group of patients with DM and no CKD, the prevalence of ECG abnormalities was 19.3%, and similar to the patients with moderate CKD and no DM (19.7%) (p=0.9). In an age matched group the prevalence of pathologic Q waves was 11.45% compared to 11.5%, respectively. Conclusion: Moderate CKD is a major risk factor for the development of the Whitehall ECG criteria which have been associated with ischemic heart disease. The importance of CKD as a risk factor for ECG abnormalities is comparable with DM. Patients with moderate CKD probably are candidates for aggressive CHD risk modification.

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APA: Copy

GHANBARIAN, A., SHAFIEI, G., RASHIDI, ARASH, & AZIZI, FEREYDOUN. (2005). COMPARISON OF ECG ABNORMALITIES IN CHRONIC KIDNEY DISEASE AND DIABETES MELLITUS: TEHRAN LIPID AND GLUCOSE STUDY (TLGS). IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 7(SUPPLEMENT 4), 449-457. SID. https://sid.ir/paper/27805/en

Vancouver: Copy

GHANBARIAN A., SHAFIEI G., RASHIDI ARASH, AZIZI FEREYDOUN. COMPARISON OF ECG ABNORMALITIES IN CHRONIC KIDNEY DISEASE AND DIABETES MELLITUS: TEHRAN LIPID AND GLUCOSE STUDY (TLGS). IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2005;7(SUPPLEMENT 4):449-457. Available from: https://sid.ir/paper/27805/en

IEEE: Copy

A. GHANBARIAN, G. SHAFIEI, ARASH RASHIDI, and FEREYDOUN AZIZI, “COMPARISON OF ECG ABNORMALITIES IN CHRONIC KIDNEY DISEASE AND DIABETES MELLITUS: TEHRAN LIPID AND GLUCOSE STUDY (TLGS),” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 7, no. SUPPLEMENT 4, pp. 449–457, 2005, [Online]. Available: https://sid.ir/paper/27805/en

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