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Information Journal Paper

Title

CORRELATION BETWEEN THE SERUM LEVELS OF URIC ACID AND HS-CRP WITH THE OCCURRENCE OF EARLY SYSTOLIC FAILURE OF LEFT VENTRICLE FOLLOWING ACUTE MYOCARDIAL INFARCTION

Pages

  531-535

Abstract

 Recent studies show that, Inflammation plays an important role in the initiation and progression of atherosclerosis and in the pathogenesis of acute cardiovascular events. There is a possible association between VENTRICULAR DYSFUNCTION following acute MYOCARDIAL INFARCTION and high Sensitivity C-REACTIVE PROTEIN (HS-CRP) and URIC ACID. In this study we assessed the relationship between HS-CRP and URIC ACID with LVEF and Killip Class in patients with acute MYOCARDIAL INFARCTION (AMI). In a cross sectional study, 188 patients (63 females and 125 males) with AMI (STEMI) who were admitted in CCU ward in Emam Khomeini Hospital, Tehran/Iran, were entered. URIC ACID and HS-CRP were measured within first day of admission. We measured ejection fraction (LVEF) and used Killip classification system. The mean age of patients was 60.4±9.2 years. The mean of URIC ACID was 5.9±1.6, 6.6±2.1, 7.1±2.1 and 9.4±1.3 in patients with Killip Class I, II, III and IV, respectively (P=0.005). The mean of HS-CRP was 1.9±1.4, 14.2±10.9, 12.2±10.9 and 15.7±6.7 in patients with Killip Class I, II, III and IV, respectively (P=0.005). There was a relationship between HS-CRP and LVEF (Correlation coefficient=-0.788, P<0.001), but there was not between URIC ACID and LVEF (Correlation coefficient=-0.111, P=0.129), The plasma concentration of C-REACTIVE PROTEIN correlated with LVEF and Killip Class in patients with AMI but serum URIC ACID was just correlated with Killip Class IV. It seems that plasma concentrations of HS-CRP and URIC ACID are useful for prediction of development of heart failure in AMI patients. More future studies are necessary for final judgment.

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    APA: Copy

    NOZARI, YOUNES, & GERAIELY, BABAK. (2011). CORRELATION BETWEEN THE SERUM LEVELS OF URIC ACID AND HS-CRP WITH THE OCCURRENCE OF EARLY SYSTOLIC FAILURE OF LEFT VENTRICLE FOLLOWING ACUTE MYOCARDIAL INFARCTION. ACTA MEDICA IRANICA, 49(8), 531-535. SID. https://sid.ir/paper/278470/en

    Vancouver: Copy

    NOZARI YOUNES, GERAIELY BABAK. CORRELATION BETWEEN THE SERUM LEVELS OF URIC ACID AND HS-CRP WITH THE OCCURRENCE OF EARLY SYSTOLIC FAILURE OF LEFT VENTRICLE FOLLOWING ACUTE MYOCARDIAL INFARCTION. ACTA MEDICA IRANICA[Internet]. 2011;49(8):531-535. Available from: https://sid.ir/paper/278470/en

    IEEE: Copy

    YOUNES NOZARI, and BABAK GERAIELY, “CORRELATION BETWEEN THE SERUM LEVELS OF URIC ACID AND HS-CRP WITH THE OCCURRENCE OF EARLY SYSTOLIC FAILURE OF LEFT VENTRICLE FOLLOWING ACUTE MYOCARDIAL INFARCTION,” ACTA MEDICA IRANICA, vol. 49, no. 8, pp. 531–535, 2011, [Online]. Available: https://sid.ir/paper/278470/en

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