Evaluation of Serum Protein Carbonyl Levels and Total Antioxidant Capacity in Patients With Basal Cell Carcinoma

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HASHEMY SEYED ISAAC; TAHERI AHMAD REZA; Behnamfard Morteza; Teimourian Mehrdad; Sabourirad Sara

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Journal: ACTA MEDICA IRANICA Year:2019 | Volume:57 | Issue:3 Page(s): 152-155

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Title

Evaluation of Serum Protein Carbonyl Levels and Total Antioxidant Capacity in Patients With Basal Cell Carcinoma

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Keywords

Basal cell carcinoma

Serum protein carbonyl

Total antioxidant capacity

Oxidative stress

Abstract

Basal cell carcinoma (BCC) is one of the most common types of human cancer. Since Oxidative stress is believed to be one of the pathogenic mechanisms involved in BCC formation, understanding the probable relation of inflammatory, oxidative factors, such as Serum protein carbonyl and Total antioxidant capacity, to BCC can help identify other pathogenic aspects of this tumor. Forty cases of BCC and forty cases of healthy controls without BCC or any other systemic disease were included in this study. After 5-ml venous blood samples were obtained from each patient, the separated serum fractions were stored at-70 C until analysis. Serum protein carbonyl level in the BCC group was significantly higher than that in the healthy controls ((5. 86± 3. 25 μ M vs. 0. 86± 0. 20 μ M, P<0. 001). The average serum Total antioxidant capacity was 3. 41± 0. 05 mM in the BCC group and 1. 15± 0. 03 mM in the control group (statistically significant at P<001). Oxidative stress might play a role in the pathogenesis of BCC.

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APA: Copy

HASHEMY, SEYED ISAAC, TAHERI, AHMAD REZA, Behnamfard, Morteza, Teimourian, Mehrdad, & Sabourirad, Sara. (2019). Evaluation of Serum Protein Carbonyl Levels and Total Antioxidant Capacity in Patients With Basal Cell Carcinoma. ACTA MEDICA IRANICA, 57(3), 152-155. SID. https://sid.ir/paper/279072/en

Vancouver: Copy

HASHEMY SEYED ISAAC, TAHERI AHMAD REZA, Behnamfard Morteza, Teimourian Mehrdad, Sabourirad Sara. Evaluation of Serum Protein Carbonyl Levels and Total Antioxidant Capacity in Patients With Basal Cell Carcinoma. ACTA MEDICA IRANICA[Internet]. 2019;57(3):152-155. Available from: https://sid.ir/paper/279072/en

IEEE: Copy

SEYED ISAAC HASHEMY, AHMAD REZA TAHERI, Morteza Behnamfard, Mehrdad Teimourian, and Sara Sabourirad, “Evaluation of Serum Protein Carbonyl Levels and Total Antioxidant Capacity in Patients With Basal Cell Carcinoma,” ACTA MEDICA IRANICA, vol. 57, no. 3, pp. 152–155, 2019, [Online]. Available: https://sid.ir/paper/279072/en

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