LONG-TERM EFFECT OF DALTEPARIN IN THE PREVENTION OF NEOVASCULARIZATION OF IRIS IN RECENT-ONSET CENTRAL RETINAL VEIN OCCLUSION

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FARAHVASH M.S.; FARAHVASH M.M.; MORADI MOGHADAM MARZIEH; MOHAMMADZADEH SHIVA

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Journal: ARCHIVES OF IRANIAN MEDICINE Year:2008 | Volume:11 | Issue:5 Page(s): 539-543

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Title

LONG-TERM EFFECT OF DALTEPARIN IN THE PREVENTION OF NEOVASCULARIZATION OF IRIS IN RECENT-ONSET CENTRAL RETINAL VEIN OCCLUSION

Author(s)

FARAHVASH M.S. | FARAHVASH M.M. | MORADI MOGHADAM MARZIEH | MOHAMMADZADEH SHIVA | Issue Writer Certificate

Keywords

CENTRAL RETINAL VEIN OCCLUSION (CRVO)

DALTEPARIN

HEPARIN

LOW MOLECULAR WEIGHT HEPARIN (LMWH)

NEOVASCULARIZATION OF IRIS (NVI)

Abstract

Background: To compare the long-term effect of DALTEPARIN in the prevention of neovascularization of iris in recent-onset central retinal vein occlusion with that of aspirin.Methods: A randomized controlled clinical trial was conducted on patients with central retinal vein occlusion of less than 30 days duration. Patients in the DALTEPARIN group received subcutaneous DALTEPARIN 100 IU/kg twice a day for 10 days, and then 100 IU/kg once a day for another ten days. In the aspirin group the patients received 100 mg aspirin daily throughout the study.Results: Forty seven patients were enrolled, 24 in the DALTEPARIN group and 23 in the aspirin group, and were followed up for one year. One (4.1%) of the 24 patients in DALTEPARIN group, and 9 (39.1%) of 23 patients in aspirin group developed iris neovascularization. the difference was significant (P=0.0001). The visual outcomes of the two groups were compared, and a significant difference was found (P=0.016).Conclusion: Patients treated with DALTEPARIN within 30 days of the onset of central retinal vein occlusion were less likely to develop neovascularization of iris. There was also a significant difference in the visual acuity between two groups.

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APA: Copy

FARAHVASH, M.S., MORADI MOGHADAM, MARZIEH, FARAHVASH, M.M., & MOHAMMADZADEH, SHIVA. (2008). LONG-TERM EFFECT OF DALTEPARIN IN THE PREVENTION OF NEOVASCULARIZATION OF IRIS IN RECENT-ONSET CENTRAL RETINAL VEIN OCCLUSION. ARCHIVES OF IRANIAN MEDICINE, 11(5), 539-543. SID. https://sid.ir/paper/280345/en

Vancouver: Copy

FARAHVASH M.S., MORADI MOGHADAM MARZIEH, FARAHVASH M.M., MOHAMMADZADEH SHIVA. LONG-TERM EFFECT OF DALTEPARIN IN THE PREVENTION OF NEOVASCULARIZATION OF IRIS IN RECENT-ONSET CENTRAL RETINAL VEIN OCCLUSION. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2008;11(5):539-543. Available from: https://sid.ir/paper/280345/en

IEEE: Copy

M.S. FARAHVASH, MARZIEH MORADI MOGHADAM, M.M. FARAHVASH, and SHIVA MOHAMMADZADEH, “LONG-TERM EFFECT OF DALTEPARIN IN THE PREVENTION OF NEOVASCULARIZATION OF IRIS IN RECENT-ONSET CENTRAL RETINAL VEIN OCCLUSION,” ARCHIVES OF IRANIAN MEDICINE, vol. 11, no. 5, pp. 539–543, 2008, [Online]. Available: https://sid.ir/paper/280345/en

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