PREDICTION OF FETAL ANEMIA BY DIFFERENT THRESHOLDS OF MCA-PSV AND DELTA-OD IN FIRST AND SECOND INTRAUTERINE TRANSFUSIONS

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RAHIMI SHARBAF FATEMEH; SHARIAT MAMAK; MIRZAIE FATEMEH; DEHGHAN PADIDEH; DASTGARDY EBRAHIM; ADABI KHADIJEH

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Journal: ARCHIVES OF IRANIAN MEDICINE Year:2012 | Volume:15 | Issue:3 Page(s): 162-165

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Title

PREDICTION OF FETAL ANEMIA BY DIFFERENT THRESHOLDS OF MCA-PSV AND DELTA-OD IN FIRST AND SECOND INTRAUTERINE TRANSFUSIONS

Author(s)

Keywords

ALLOIMMUNIZATION

AMNIOCENTESIS

DOPPLER ULTRASONOGRAPHY

INTRAUTERINE TRANSFUSION

FETAL ANEMIA

MIDDLE CEREBRAL ARTERY

Abstract

Background: Our aim was to compare different thresholds of MIDDLE CEREBRAL ARTERY peak systolic velocity (MCA-PSV) and amniotic fluid delta optical density (Delta-OD) with fetal hemoglobin (Hb) duringfirst and second INTRAUTERINE TRANSFUSIONs (IUT).Methods: We determined serial MCA-PSV and Delta-OD in 27 red blood cell alloimmunized fetuses who needed IUT. Before the second IUT, MCA-PSV was measured. The sensitivity and specificity of MCA-PSV and Delta-OD were calculated and compared with fetal hemoglobin levels.Results: From 27 fetuses, first time IUT MCA-PSV with a normal median value (MOM) cutoff of>1.29 detected 60% of the moderate and 100% of the severe anemia cases. MCA-PSV of MOM>1.5 detected none of the moderate and 93% of severe anemia cases. Delta-OD detected 50% of moderate anemic and 80% of severe anemic cases. At the second IUT, 91% of severe anemia cases were confirmed by MCA-PSV with MOM>1.5 whereas MCA-PSV with MOM>1.29 confirmed all cases. One case of moderate anemia was detected by MCA-PSV of MOM>1.29 and none were detected by MCA-PSV with MOM>1.5.Conclusion: Different thresholds of MCA-PSV have higher sensitivity and specificity for detecting moderate and severe FETAL ANEMIA compared with Delta-OD. It also has a high sensitivity at the second IUT.

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APA: Copy

RAHIMI SHARBAF, FATEMEH, SHARIAT, MAMAK, MIRZAIE, FATEMEH, DEHGHAN, PADIDEH, DASTGARDY, EBRAHIM, & ADABI, KHADIJEH. (2012). PREDICTION OF FETAL ANEMIA BY DIFFERENT THRESHOLDS OF MCA-PSV AND DELTA-OD IN FIRST AND SECOND INTRAUTERINE TRANSFUSIONS. ARCHIVES OF IRANIAN MEDICINE, 15(3), 162-165. SID. https://sid.ir/paper/280746/en

Vancouver: Copy

RAHIMI SHARBAF FATEMEH, SHARIAT MAMAK, MIRZAIE FATEMEH, DEHGHAN PADIDEH, DASTGARDY EBRAHIM, ADABI KHADIJEH. PREDICTION OF FETAL ANEMIA BY DIFFERENT THRESHOLDS OF MCA-PSV AND DELTA-OD IN FIRST AND SECOND INTRAUTERINE TRANSFUSIONS. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2012;15(3):162-165. Available from: https://sid.ir/paper/280746/en

IEEE: Copy

FATEMEH RAHIMI SHARBAF, MAMAK SHARIAT, FATEMEH MIRZAIE, PADIDEH DEHGHAN, EBRAHIM DASTGARDY, and KHADIJEH ADABI, “PREDICTION OF FETAL ANEMIA BY DIFFERENT THRESHOLDS OF MCA-PSV AND DELTA-OD IN FIRST AND SECOND INTRAUTERINE TRANSFUSIONS,” ARCHIVES OF IRANIAN MEDICINE, vol. 15, no. 3, pp. 162–165, 2012, [Online]. Available: https://sid.ir/paper/280746/en

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