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Information Journal Paper

Title

XEROSTOMIA AFTER RADIOTHERAPY AND ITS EFFECT ON QUALITY OF LIFE IN HEAD AND NECK CANCER PATIENTS

Pages

  214-218

Abstract

 BACKGROUND: XEROSTOMIA is one of the one complications following RADIOTHERAPY that can affect QUALITY OF LIFE (QoL). This study aims to assess the severity of XEROSTOMIA in patients with head and neck cancers after RADIOTHERAPY and its effect on QoL.METHODS: In this longitudinal prospective study, the severity of XEROSTOMIA and related QoL were was assessed in 63 head and neck cancer patients who referred to the RADIOTHERAPY Ward. Patients completed a XEROSTOMIA questionnaire (XQ) at the beginning, and 2, 4, and 6 weeks after treatment over a period of 6 months. Additionally, unstimulated saliva was collected using the spitting method at all 4 visits.RESULTS: QoL significantly worsened with increased time (P = 0.0001), meanwhile, the severity of XEROSTOMIA increased significantly (P = 0.0001). However, there was no significant change in the amount of saliva at these 4 time points (P = 0.23). Regression analysis showed that with each milliliter decrease in saliva secretion, the QoL score decreased 2.25%. With one score increase in XEROSTOMIA, from the QoL mean score there was a 1.65% decrease.CONCLUSION: The decrease in saliva and XEROSTOMIA that resulted from RADIOTHERAPY plays an important role in worsening QoL among patients who undergo RADIOTHERAPY for head and neck cancers. Although the amount of saliva has a significant association with QoL, the XEROSTOMIA score which shows subjects' general feeling also independently impacts QoL. In future studies, we recommend patient assessments for periods longer than 6 months.

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    APA: Copy

    KAKOEI, SHAHLA, HAGHDOOST, ALI AKBAR, RAD, MARYAM, MOHAMMADALIZADEH, SAKINEH, POURDAMGHAN, NASIM, NAKHAEI, MAHDIEH, & BAHADOR, MARYAM. (2012). XEROSTOMIA AFTER RADIOTHERAPY AND ITS EFFECT ON QUALITY OF LIFE IN HEAD AND NECK CANCER PATIENTS. ARCHIVES OF IRANIAN MEDICINE, 15(4), 214-218. SID. https://sid.ir/paper/280818/en

    Vancouver: Copy

    KAKOEI SHAHLA, HAGHDOOST ALI AKBAR, RAD MARYAM, MOHAMMADALIZADEH SAKINEH, POURDAMGHAN NASIM, NAKHAEI MAHDIEH, BAHADOR MARYAM. XEROSTOMIA AFTER RADIOTHERAPY AND ITS EFFECT ON QUALITY OF LIFE IN HEAD AND NECK CANCER PATIENTS. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2012;15(4):214-218. Available from: https://sid.ir/paper/280818/en

    IEEE: Copy

    SHAHLA KAKOEI, ALI AKBAR HAGHDOOST, MARYAM RAD, SAKINEH MOHAMMADALIZADEH, NASIM POURDAMGHAN, MAHDIEH NAKHAEI, and MARYAM BAHADOR, “XEROSTOMIA AFTER RADIOTHERAPY AND ITS EFFECT ON QUALITY OF LIFE IN HEAD AND NECK CANCER PATIENTS,” ARCHIVES OF IRANIAN MEDICINE, vol. 15, no. 4, pp. 214–218, 2012, [Online]. Available: https://sid.ir/paper/280818/en

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