FULMINANT TYPE 1 AUTOIMMUNE HEPATITIS IN A RECENTLY DIAGNOSED CELIAC DISEASE PATIENT (CASE REPORT)

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VOLTA UMBERTO; ROSTAMI KAMRAN; TOVOLI FRANCESCO; CAIO GIACOMO; MASI CHIARA; RUGGERI EUGENIO; CACCIARI GIULIA; ISABELLA BON; GIORGIO ROBERTO DE

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Journal: ARCHIVES OF IRANIAN MEDICINE Year:2013 | Volume:16 | Issue:11 Page(s): 683-685

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Title

FULMINANT TYPE 1 AUTOIMMUNE HEPATITIS IN A RECENTLY DIAGNOSED CELIAC DISEASE PATIENT (CASE REPORT)

Author(s)

Keywords

ANTINUCLEAR ANTIBODIES

ANTISMOOTH MUSCLE ANTIBODIES

AUTOIMMUNE HEPATITIS

CELIAC DISEASE

LIVER TRANSPLANTATION

Abstract

Celiac disease (CD) is a small intestine immune-mediated disorder triggered by gluten ingestion in genetically predisposed patients. This condition can also affect many extraintestinal tissues, including the liver.We report a patient presenting with a marked increase of transaminases at diagnosis of CD. The immune markers for AUTOIMMUNE HEPATITIS (AIH) were negative. Following a few months of a strict gluten-free diet (GFD), aminotransferase levels decreased significantly (<2.5x U/L). The response to GFD suggested that the liver damage was due to a gluten-dependent celiac hepatitis, the most common liver abnormality in CD. Despite the fact that the patient never stopped the GFD, yet, in a few months, the aminotransferase levels raise again to high values (>50x U/L). At this time, the liver autoantibodies turned to be positive thus confirming the development of a type 1 AIH. The hepatic damage progressed to a late onset liver failure requiring LIVER TRANSPLANTATION.

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APA: Copy

VOLTA, UMBERTO, ROSTAMI, KAMRAN, TOVOLI, FRANCESCO, CAIO, GIACOMO, MASI, CHIARA, RUGGERI, EUGENIO, CACCIARI, GIULIA, ISABELLA, BON, & GIORGIO, ROBERTO DE. (2013). FULMINANT TYPE 1 AUTOIMMUNE HEPATITIS IN A RECENTLY DIAGNOSED CELIAC DISEASE PATIENT (CASE REPORT). ARCHIVES OF IRANIAN MEDICINE, 16(11), 683-685. SID. https://sid.ir/paper/281107/en

Vancouver: Copy

VOLTA UMBERTO, ROSTAMI KAMRAN, TOVOLI FRANCESCO, CAIO GIACOMO, MASI CHIARA, RUGGERI EUGENIO, CACCIARI GIULIA, ISABELLA BON, GIORGIO ROBERTO DE. FULMINANT TYPE 1 AUTOIMMUNE HEPATITIS IN A RECENTLY DIAGNOSED CELIAC DISEASE PATIENT (CASE REPORT). ARCHIVES OF IRANIAN MEDICINE[Internet]. 2013;16(11):683-685. Available from: https://sid.ir/paper/281107/en

IEEE: Copy

UMBERTO VOLTA, KAMRAN ROSTAMI, FRANCESCO TOVOLI, GIACOMO CAIO, CHIARA MASI, EUGENIO RUGGERI, GIULIA CACCIARI, BON ISABELLA, and ROBERTO DE GIORGIO, “FULMINANT TYPE 1 AUTOIMMUNE HEPATITIS IN A RECENTLY DIAGNOSED CELIAC DISEASE PATIENT (CASE REPORT),” ARCHIVES OF IRANIAN MEDICINE, vol. 16, no. 11, pp. 683–685, 2013, [Online]. Available: https://sid.ir/paper/281107/en

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