ARDEH (SESAMUM INDICUM) COULD IMPROVE SERUM TRIGLYCERIDES AND ATHEROGENIC LIPID PARAMETERS IN TYPE 2 DIABETIC PATIENTS: A RANDOMIZED CLINICAL TRIAL

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MIRMIRAN PARVIN; BAHADORAN ZAHRA; GOLZARAND MAHDIEH; RAJAB ASADOLAH; AZIZI FEREIDOUN

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Journal: ARCHIVES OF IRANIAN MEDICINE Year:2013 | Volume:16 | Issue:11 Page(s): 652-656

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Title

ARDEH (SESAMUM INDICUM) COULD IMPROVE SERUM TRIGLYCERIDES AND ATHEROGENIC LIPID PARAMETERS IN TYPE 2 DIABETIC PATIENTS: A RANDOMIZED CLINICAL TRIAL

Author(s)

Keywords

ARDEH

LIPID PROFILES

SESAME SEEDS

TYPE 2 DIABETES

Abstract

BACKGROUND: Data suggest that SESAME SEEDS have properties beneficial to modulating lipid disorders and decreasing cardiovascular disease (CVD) risk factors. The aim of this study was to investigate the effects of ARDEH, paste of ground unhulled SESAME SEEDS, on LIPID PROFILES and atherogenic lipid parameters. METHODS: This randomized clinical trial included 41 patients with TYPE 2 DIABETES, who were randomly assigned to one of the two groups: group A (ARDEH 28 g/d, n=21) and group B (control, n=20). After an initial two-week washout period, the patients in group A, replaced a part of their usual breakfast with two tablespoon (tbsp) (~28 g) ARDEH, while group B patients continued the usual breakfast meal for six weeks; energy content of both breakfast meals was maintained in the same range. Anthropometric measures, blood pressure, serum levels of total cholesterol (TC), triglycerides (TG), LDL-C, HDL-C, and atherogenic index of plasma (AIP; log TG/HDL-C), TC/HDL-C ratio, and LDL/HDL-C ratio were determined at baseline and six weeks later. RESULTS: After six weeks, there were significant decreases in serum TG (15.3 mg/dL) and AIP (39%) in group A. Moreover, slight decreases in serum TC, LDL-C, and other atherogenic lipid parameters and a mild increase in HDL-C also were observed during ARDEH supplementation. Anthropometric measures and blood pressure were unchanged during the study period in both groups. CONCLUSION: ARDEH could have favorable effects in decreasing CVD risk factors in type 2 diabetics.

Cites

EFFECTS OF SESAME SEED CONSUMPTION ON ANTHROPOMETRIC INDICES, LIPID PROFILE AND ATHEROGENIC INDEX OF PLASMA IN WOMEN WITH METABOLIC SYNDROME

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APA: Copy

MIRMIRAN, PARVIN, BAHADORAN, ZAHRA, GOLZARAND, MAHDIEH, RAJAB, ASADOLAH, & AZIZI, FEREIDOUN. (2013). ARDEH (SESAMUM INDICUM) COULD IMPROVE SERUM TRIGLYCERIDES AND ATHEROGENIC LIPID PARAMETERS IN TYPE 2 DIABETIC PATIENTS: A RANDOMIZED CLINICAL TRIAL. ARCHIVES OF IRANIAN MEDICINE, 16(11), 652-656. SID. https://sid.ir/paper/281112/en

Vancouver: Copy

MIRMIRAN PARVIN, BAHADORAN ZAHRA, GOLZARAND MAHDIEH, RAJAB ASADOLAH, AZIZI FEREIDOUN. ARDEH (SESAMUM INDICUM) COULD IMPROVE SERUM TRIGLYCERIDES AND ATHEROGENIC LIPID PARAMETERS IN TYPE 2 DIABETIC PATIENTS: A RANDOMIZED CLINICAL TRIAL. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2013;16(11):652-656. Available from: https://sid.ir/paper/281112/en

IEEE: Copy

PARVIN MIRMIRAN, ZAHRA BAHADORAN, MAHDIEH GOLZARAND, ASADOLAH RAJAB, and FEREIDOUN AZIZI, “ARDEH (SESAMUM INDICUM) COULD IMPROVE SERUM TRIGLYCERIDES AND ATHEROGENIC LIPID PARAMETERS IN TYPE 2 DIABETIC PATIENTS: A RANDOMIZED CLINICAL TRIAL,” ARCHIVES OF IRANIAN MEDICINE, vol. 16, no. 11, pp. 652–656, 2013, [Online]. Available: https://sid.ir/paper/281112/en

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