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Title

ADVERSE CUTANEOUS DRUG REACTIONS - A CLINICO-DEMOGRAPHIC STUDY IN A TERTIARY CARE TEACHING HOSPITAL OF THE KASHMIR VALLEY, INDIA

Pages

  228-233

Abstract

 BACKGROUND: ADVERSE CUTANEOUS DRUG REACTIONS (ACDRs) are caused by a wide variety of agents. The aim was to study the incidence and clinico-demographic profile of ACDRs to identify any potential risk factors and compare the results with other studies.METHODS: A cross-sectional observational study was conducted over a period of one year from October 2012 to October 2013 in the outpatient department (OPD) of a tertiary care teaching hospital of the Kashmir valley in India and various ACDRs were recorded.RESULTS: The incidence of ACDRs was 0.16%. The mean age of patients was 39.36±16.77 years. The male: female ratio was 0.97:1. The most frequently reported cutaneous reactions were with antimicrobials (57.33%) followed by NSAIDs (21.33%) and antiepileptic drugs (17.33%). Less common groups involved were steroids, antipsychotics and bisphosphonates (1.33% each). Fixed drug eruptions (FDEs) were the commonest (45.33%) followed by maculopapular (17.33%), photoallergic (8%), erythema multiforme (6.66%), Stevens-Johnson syndrome (5.33%) and lichenoid eruptions (4%). Less common patterns were urticaria, Drug Reaction with Eosinophilia and systemic symptoms (DRESS syndrome) and acneform eruptions (2.66% each) followed by angioedema, acute generalized exanthematous pustulosis (AGEP), exfoliative dermatitis and toxic epidermal necrolysis (1.33% each).CONCLUSION: Physicians should have adequate knowledge of ADVERSE DRUG REACTIONS, especially of newer drugs which are increasing every year in order to minimize such events.

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    APA: Copy

    QAYOOM, SEEMA, BISATI, SHAZIA, MANZOOR, SHEIKH, SAMEEM, FARAH, & KHAN, KAFEEL. (2015). ADVERSE CUTANEOUS DRUG REACTIONS - A CLINICO-DEMOGRAPHIC STUDY IN A TERTIARY CARE TEACHING HOSPITAL OF THE KASHMIR VALLEY, INDIA. ARCHIVES OF IRANIAN MEDICINE, 18(4), 228-233. SID. https://sid.ir/paper/281221/en

    Vancouver: Copy

    QAYOOM SEEMA, BISATI SHAZIA, MANZOOR SHEIKH, SAMEEM FARAH, KHAN KAFEEL. ADVERSE CUTANEOUS DRUG REACTIONS - A CLINICO-DEMOGRAPHIC STUDY IN A TERTIARY CARE TEACHING HOSPITAL OF THE KASHMIR VALLEY, INDIA. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2015;18(4):228-233. Available from: https://sid.ir/paper/281221/en

    IEEE: Copy

    SEEMA QAYOOM, SHAZIA BISATI, SHEIKH MANZOOR, FARAH SAMEEM, and KAFEEL KHAN, “ADVERSE CUTANEOUS DRUG REACTIONS - A CLINICO-DEMOGRAPHIC STUDY IN A TERTIARY CARE TEACHING HOSPITAL OF THE KASHMIR VALLEY, INDIA,” ARCHIVES OF IRANIAN MEDICINE, vol. 18, no. 4, pp. 228–233, 2015, [Online]. Available: https://sid.ir/paper/281221/en

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