PEDIATRIC REFERENCE VALUES FOR SERUM CREATININE AND ESTIMATED GLOMERULAR FILTRATION RATE IN IRANIANS: TEHRAN LIPID AND GLUCOSE STUDY

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GHASEMI ASGHAR; AZIMZADEH IRAJ; AFGHAN MARJAN; MOMENAN AMIR ABBAS; BAGHERIPOUR FATEMEH; AZIZI FEREIDOUN

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Journal: ARCHIVES OF IRANIAN MEDICINE Year:2015 | Volume:18 | Issue:11 Page(s): 753-759

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Title

PEDIATRIC REFERENCE VALUES FOR SERUM CREATININE AND ESTIMATED GLOMERULAR FILTRATION RATE IN IRANIANS: TEHRAN LIPID AND GLUCOSE STUDY

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Keywords

CHILD

JAFFE

REFERENCE VALUES

SERUM CREATININE

Abstract

METHODS: SERUM CREATININE of 1594 subjects, aged 3 – 18 years, participating in phase 4 of the Tehran Lipid and Glucose Study (2008 – 2011) was measured using the conventional JAFFE method. The non-parametric method of Schwartz and Counahan-Barratt equations were used to calculate eGFR. CLSI/IFCC guidelines were used to determine REFERENCE VALUES.RESULTS: In both genders, SERUM CREATININE concentration was significantly increased with age and had a positive correlation with age (boys (r = 0.786, n = 778, P < 0.001) and girls (r = 0.638, n = 724, P < 0.001)). In addition, mean SERUM CREATININE concentration was significantly higher in boys, compared to girls (0.86±0.01 vs. 0.80±0.01 mg/dL, P < 0.001). Based on these results, we proposed the following formula: SERUM CREATININE (mg/dL)=k´age (year)+0.5, where k was 0.03 for boys and 0.02 for girls.CONCLUSIONS: This study presents pediatric REFERENCE VALUES in Iranian boys and girls for SERUM CREATININE levels to be 0.6 – 1.20 mg/dL and 0.6 – 1.00 mg/dL and for eGFR values to be 81 – 154 mL/min/1.73 m2 and 80 – 129 mL/min/1.73 m2, respectively. These values can be used for diagnostic and therapeutic purposes.

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APA: Copy

GHASEMI, ASGHAR, AZIMZADEH, IRAJ, AFGHAN, MARJAN, MOMENAN, AMIR ABBAS, BAGHERIPOUR, FATEMEH, & AZIZI, FEREIDOUN. (2015). PEDIATRIC REFERENCE VALUES FOR SERUM CREATININE AND ESTIMATED GLOMERULAR FILTRATION RATE IN IRANIANS: TEHRAN LIPID AND GLUCOSE STUDY. ARCHIVES OF IRANIAN MEDICINE, 18(11), 753-759. SID. https://sid.ir/paper/281301/en

Vancouver: Copy

GHASEMI ASGHAR, AZIMZADEH IRAJ, AFGHAN MARJAN, MOMENAN AMIR ABBAS, BAGHERIPOUR FATEMEH, AZIZI FEREIDOUN. PEDIATRIC REFERENCE VALUES FOR SERUM CREATININE AND ESTIMATED GLOMERULAR FILTRATION RATE IN IRANIANS: TEHRAN LIPID AND GLUCOSE STUDY. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2015;18(11):753-759. Available from: https://sid.ir/paper/281301/en

IEEE: Copy

ASGHAR GHASEMI, IRAJ AZIMZADEH, MARJAN AFGHAN, AMIR ABBAS MOMENAN, FATEMEH BAGHERIPOUR, and FEREIDOUN AZIZI, “PEDIATRIC REFERENCE VALUES FOR SERUM CREATININE AND ESTIMATED GLOMERULAR FILTRATION RATE IN IRANIANS: TEHRAN LIPID AND GLUCOSE STUDY,” ARCHIVES OF IRANIAN MEDICINE, vol. 18, no. 11, pp. 753–759, 2015, [Online]. Available: https://sid.ir/paper/281301/en

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