مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

274
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

228
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

1

Information Journal Paper

Title

EFFECTS OF PROBIOTIC SUPPLEMENTATION ON HORMONAL PROFILES, BIOMARKERS OF INFLAMMATION AND OXIDATIVE STRESS IN WOMEN WITH POLYCYSTIC OVARY SYNDROME: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

Pages

  1-7

Abstract

 Background: To the best of our knowledge, data on effects of PROBIOTIC administration on HORMONAL PROFILES, biomarkers of INFLAMMATION and OXIDATIVE STRESS in women with POLYCYSTIC OVARY SYNDROME (PCOS) are scarce. This investigation was conducted to assess the effects of PROBIOTIC supplementation on HORMONAL PROFILES, biomarkers of INFLAMMATION and OXIDATIVE STRESS in women with PCOS. Methods: This randomized, double-blind, placebo-controlled trial was conducted on 60 women with PCOS, aged 18-40 years old. Subjects were randomly assigned into 2 groups to receive either PROBIOTICs or placebo (n = 30 each group) for 12 weeks. Metabolic profiles were quantified at baseline and after a 12-week intervention. Results: After the 12-week intervention, compared with placebo, PROBIOTIC supplementation significantly increased serum sex hormone-binding globulin (SHBG) (+25. 9 ± 32. 5 vs. +0. 5 ± 15. 6 nmol/L, P < 0. 001) and plasma total antioxidant capacity (TAC) (+8. 8 ± 120. 5 vs.-98. 3 ± 246. 4 mmol/L, P = 0. 04), and significantly decreased serum total testosterone (-0. 2 ± 0. 7 vs. +0. 2 ± 0. 6 ng/mL, P = 0. 03), modified Ferriman-Gallwey (mF-G) scores (-1. 7 ± 1. 5 vs.-0. 2 ± 1. 0, P < 0. 001), serum high-sensitivity C-reactive protein (hs-CRP) (-1150. 0 ± 1295. 2 vs. +202. 5 ± 1426. 3 ng/mL, P < 0. 001) and plasma malondialdehyde (MDA) concentrations (-0. 2 ± 0. 6 vs. +0. 9 ± 1. 3 μ mol/L, P < 0. 001). We did not observe any detrimental effect of PROBIOTIC supplementation on other metabolic profiles. Conclusion: Overall, PROBIOTIC supplementation of PCOS women for 12 weeks had beneficial effects on total testosterone, SHBG, mFG scores, hs-CRP, TAC and MDA levels but did not affect other metabolic profiles.

Cites

References

  • No record.

    • Cite

    APA: Copy

    KARAMALI, MARYAM, EGHBALPOUR, SARA, RAJABI, SAJAD, JAMILIAN, MEHRI, BAHMANI, FERESHTEH, TAJABADI EBRAHIMI, MARYAM, KENESHLOU, FARIBA, MIRHASHEMI, SEYYED MEHDI, CHAMANI, MARYAM, HASHEM GELOUGERDI, SARA, & ASEMI, ZATOLLAH. (2018). EFFECTS OF PROBIOTIC SUPPLEMENTATION ON HORMONAL PROFILES, BIOMARKERS OF INFLAMMATION AND OXIDATIVE STRESS IN WOMEN WITH POLYCYSTIC OVARY SYNDROME: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL. ARCHIVES OF IRANIAN MEDICINE, 21(1), 1-7. SID. https://sid.ir/paper/281594/en

    Vancouver: Copy

    KARAMALI MARYAM, EGHBALPOUR SARA, RAJABI SAJAD, JAMILIAN MEHRI, BAHMANI FERESHTEH, TAJABADI EBRAHIMI MARYAM, KENESHLOU FARIBA, MIRHASHEMI SEYYED MEHDI, CHAMANI MARYAM, HASHEM GELOUGERDI SARA, ASEMI ZATOLLAH. EFFECTS OF PROBIOTIC SUPPLEMENTATION ON HORMONAL PROFILES, BIOMARKERS OF INFLAMMATION AND OXIDATIVE STRESS IN WOMEN WITH POLYCYSTIC OVARY SYNDROME: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2018;21(1):1-7. Available from: https://sid.ir/paper/281594/en

    IEEE: Copy

    MARYAM KARAMALI, SARA EGHBALPOUR, SAJAD RAJABI, MEHRI JAMILIAN, FERESHTEH BAHMANI, MARYAM TAJABADI EBRAHIMI, FARIBA KENESHLOU, SEYYED MEHDI MIRHASHEMI, MARYAM CHAMANI, SARA HASHEM GELOUGERDI, and ZATOLLAH ASEMI, “EFFECTS OF PROBIOTIC SUPPLEMENTATION ON HORMONAL PROFILES, BIOMARKERS OF INFLAMMATION AND OXIDATIVE STRESS IN WOMEN WITH POLYCYSTIC OVARY SYNDROME: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL,” ARCHIVES OF IRANIAN MEDICINE, vol. 21, no. 1, pp. 1–7, 2018, [Online]. Available: https://sid.ir/paper/281594/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button