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Information Journal Paper

Title

Reference Values for Serum Lipid Profiles in Iranian Adults: Tehran Lipid and Glucose Study

Pages

  24-31

Abstract

 Background: Lipid abnormalities are major risk factors for cardiovascular diseases. In addition to age and sex, other variables can affect serum Lipid levels, warranting the determination of population-specific Reference values. This study aimed to determine age-and sex-specific Reference values for serum total Cholesterol (TC), low-density lipoprotein-Cholesterol (LDL-C), high-density lipoprotein-Cholesterol (HDL-C), and Triglycerides (TG) in healthy Tehranian adults. Methods: TC, TG, and HDL-C were measured using the enzymatic colorimetric method and the Friedewald equation (LDL-C = TC − HDL-C − TG/5) was used to calculate LDL-C concentrations in individuals with TG <400 mg/dL. After applying the exclusion criteria, 1147 participants (548 men and 599 women) aged ≥ 20 years were included. For determining Reference values, the International Federation of Clinical Chemistry guidelines (non-parametric method) and the robust method were used for sample sizes ≥ 120 and <120, respectively. Results: Reference values for serum TC, LDL-C, HDL-C, and TG were 121. 0– 261. 0, 54. 1– 175. 2, 30. 9– 71. 9, and 46. 9– 301. 2 mg/dL in men and 117. 8– 235. 9, 49. 9– 160. 9, 36. 0– 83. 9, and 38. 1– 184. 2 mg/dL in women, respectively. All parameters except HDL-C were higher in men than women and showed an increasing trend with age. Conclusion: Reference values for serum TC, LDL-C, HDL-C, and TG in healthy Tehranian adults were determined, and these values could provide the basis for better decision making in both prevention and clinical settings.

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    APA: Copy

    RAHMANI, MARYAM, JEDDI, SAJAD, Ghanbari, Mahboubeh, MOMENAN, AMIR ABBAS, AZIZI, FEREIDOUN, & GHASEMI, ASGHAR. (2019). Reference Values for Serum Lipid Profiles in Iranian Adults: Tehran Lipid and Glucose Study. ARCHIVES OF IRANIAN MEDICINE, 22(1), 24-31. SID. https://sid.ir/paper/281763/en

    Vancouver: Copy

    RAHMANI MARYAM, JEDDI SAJAD, Ghanbari Mahboubeh, MOMENAN AMIR ABBAS, AZIZI FEREIDOUN, GHASEMI ASGHAR. Reference Values for Serum Lipid Profiles in Iranian Adults: Tehran Lipid and Glucose Study. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2019;22(1):24-31. Available from: https://sid.ir/paper/281763/en

    IEEE: Copy

    MARYAM RAHMANI, SAJAD JEDDI, Mahboubeh Ghanbari, AMIR ABBAS MOMENAN, FEREIDOUN AZIZI, and ASGHAR GHASEMI, “Reference Values for Serum Lipid Profiles in Iranian Adults: Tehran Lipid and Glucose Study,” ARCHIVES OF IRANIAN MEDICINE, vol. 22, no. 1, pp. 24–31, 2019, [Online]. Available: https://sid.ir/paper/281763/en

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