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Title

PHOTOPRODUCTS OF INDOMETHACIN

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  0-0

Abstract

 In a photochemical chamber, a sample of 27.9 mM indomethacin (IN) in methanol was exposed to a Philips 400-W UV lamp for 5 days in normal atmosphere. Four photoproducts were separated using high-performance liquid chromatography, and their structures were elucidated by various spectroscopic methods, including liquid chromatography–electrospray ionization–mass spectrometry. A reaction scheme of IN in methanol is proposed: The photochemical reaction routes occur mainly via esterification and decarboxylation, followed by oxidation with singlet oxygen to produce an aldehyde. A b-hydroxy-g-lactone was also formed through a photochemical [2 + 2] cycloaddition, and its structure was confirmed by single-crystal X-ray diffraction.

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    APA: Copy

    LIN, PEN YUAN, CHEN, FU AN, WU, AN BANG, CHAO, SU HUI, PENG, YU TANG, LEE, VICKIE M.H., & CHEN, CHAU YANG. (2016). PHOTOPRODUCTS OF INDOMETHACIN. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS), 13(10), 0-0. SID. https://sid.ir/paper/283247/en

    Vancouver: Copy

    LIN PEN YUAN, CHEN FU AN, WU AN BANG, CHAO SU HUI, PENG YU TANG, LEE VICKIE M.H., CHEN CHAU YANG. PHOTOPRODUCTS OF INDOMETHACIN. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS)[Internet]. 2016;13(10):0-0. Available from: https://sid.ir/paper/283247/en

    IEEE: Copy

    PEN YUAN LIN, FU AN CHEN, AN BANG WU, SU HUI CHAO, YU TANG PENG, VICKIE M.H. LEE, and CHAU YANG CHEN, “PHOTOPRODUCTS OF INDOMETHACIN,” JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS), vol. 13, no. 10, pp. 0–0, 2016, [Online]. Available: https://sid.ir/paper/283247/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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