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Information Journal Paper

Title

THE RADIOLOGICAL SPECTRUM OF PULMONARY MULTIDRUG-RESISTANT TUBERCULOSIS IN HIV-NEGATIVE PATIENTS

Pages

  161-166

Abstract

 Background: MULTIDRUG-RESISTANT TUBERCULOSIS (MDR-TB) is a major worldwide health problem. In countries where TB is of moderate to high prevalence, the issue of MDR-TB carries significant importance. MDR-TB, similar to drug-sensitive TB, is contagious. Meanwhile its treatment is not only more difficult but also more expensive with lower success rates. Regarding clinical findings, there is no significant difference between MDR-TB and drug-sensitive TB. Therefore determination of characteristic radiological findings in cases of MDR-TB might be of help in early detection, and hence appropriate management of this disease condition. Objective: To explain the radiological spectrum of PULMONARY MDR-TB. Patients and Methods: We retrospectively evaluated the radiographic images of 35 patients with clinically- and microbiologically-proven MDR-TB admitted to our tertiary-care TB unit over a period of 13 months. The latest chest X-RAY of all patients and the conventional chest CT scan without contrast of 15 patients were reviewed by three expert radiologists who rendered consensus opinion. Results: Of the 35 patients with imaging studies, 23 (66%) were male and 12 (34%) were female. The mean±SD age of participants was 38.2±17.3 (range: 16–80) years. 33 patients were known as secondary and only 2 had primary MDR-TB. Chest radiography revealed cavitary lesion in 80%, PULMONARY infiltration in 89% and nodules in 80% of the cases. Pleurisy was the rarest finding observed in only 5 (14%) patients. All of 15 chest CT scans revealed cavitation, 93% of which were bilateral and multiple. Pleural involvement was seen in 93% of patients. Conclusion: Presence of multiple cavities, especially in lungs, nodular and infiltrative lesions, and pleural effusion are main features of MDR-TB as compared to drug-sensitive TB.

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    APA: Copy

    ZAHIRIFARD, S., AMIRI, M.V., BAKHSHAYESH KARAM, M., MIRSAEIDI, SEYED MAHDI, EHSANPOUR, A., & MASJEDI, M.R.. (2003). THE RADIOLOGICAL SPECTRUM OF PULMONARY MULTIDRUG-RESISTANT TUBERCULOSIS IN HIV-NEGATIVE PATIENTS. IRANIAN JOURNAL OF RADIOLOGY, 1(3-4), 161-166. SID. https://sid.ir/paper/283543/en

    Vancouver: Copy

    ZAHIRIFARD S., AMIRI M.V., BAKHSHAYESH KARAM M., MIRSAEIDI SEYED MAHDI, EHSANPOUR A., MASJEDI M.R.. THE RADIOLOGICAL SPECTRUM OF PULMONARY MULTIDRUG-RESISTANT TUBERCULOSIS IN HIV-NEGATIVE PATIENTS. IRANIAN JOURNAL OF RADIOLOGY[Internet]. 2003;1(3-4):161-166. Available from: https://sid.ir/paper/283543/en

    IEEE: Copy

    S. ZAHIRIFARD, M.V. AMIRI, M. BAKHSHAYESH KARAM, SEYED MAHDI MIRSAEIDI, A. EHSANPOUR, and M.R. MASJEDI, “THE RADIOLOGICAL SPECTRUM OF PULMONARY MULTIDRUG-RESISTANT TUBERCULOSIS IN HIV-NEGATIVE PATIENTS,” IRANIAN JOURNAL OF RADIOLOGY, vol. 1, no. 3-4, pp. 161–166, 2003, [Online]. Available: https://sid.ir/paper/283543/en

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