EVALUATING THE PREVALENCE OF HYPOGONADOTROPIC AMENORRHEA IN INFERTILE WOMEN AND THE RATE OF PREGNANCY FOLLOWING TREATMENT

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TORABIZADEH A.; VAHID ROUDSARI FATEMEH

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Journal: Journal of Reproduction & Infertility Year:2005 | Volume:6 | Issue:3 (23) Page(s): 247-253

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Title

EVALUATING THE PREVALENCE OF HYPOGONADOTROPIC AMENORRHEA IN INFERTILE WOMEN AND THE RATE OF PREGNANCY FOLLOWING TREATMENT

Author(s)

TORABIZADEH A. | VAHID ROUDSARI FATEMEH | Issue Writer Certificate

Keywords

PRIMARY AMENORRHEAQ3

HYPOGONADOTROPIC INFERTILITYQ3

GONADOTROPINQ2

HMGQ3

PROLACTINQ2

INTRAUTERINE INSEMINATIONQ2

Abstract

Introduction: Hypogonadotropic amenorrhea is one kind of PRIMARY AMENORRHEA which is caused by a decrease in GnRH secretion and results in infertility. As infertility is an important problem in 10-15% of couples, the present study was undertaken to determine the prevalence of the disease in infertile women and pregnancy rates in response to its treatment. Materials and Methods: This cross-sectional, analytical study included 35 subjects suffering from hypothalamic amenorrhea, pulled from 2150 patients who referred to the infertility center of Montaserieh Hospital in Mashad during 2000-2002. The gathered data included: the patients age, infertility duration, menstrual cycles, history of prior surgeries or illnesses, food regimens and drug history. A gynecologic exam, hormonal assays and sonographic evaluations were carried out. The patients underwent 3 cycles of ovulation induction procedures. A serum β -hCG measurement and a vaginal sonography were used to confirm pregnancy. The data were analyzed by SPSS 11. For the descriptive analysis, t-test and logistic regression were used and the significance level was considered 5% (p<0.05). Results: The patients aged 20-35 and their infertility period varied from 1.5 to 14 years. Three of them were excluded from the study because of loss to follow up. The prevalence rate was 1-6%. In all of the patients, the serum FSH and LH levels were <5IU/ml. Serum PROLACTIN levels were 21.7%±34.8 IU/ml and TSH 1.2±0.6 IU/ml. 14 patients out of 32, responded to treatment and became pregnant after three cycles of treatment (43.7%). Conclusion: The prevalence rate of infertility due to hypogonadotropic amenorrhea in this study was 0.016. Infertility due to hypogonadotropic amenorrhea is a disease that can respond to common ovulation induction treatment schedules quite well and despite the short period of treatment (3 cycles) in this study, 43.7% of the patients became pregnant. It is expected that by increasing the treatment period, better results will follow as it has in studies following 6 cycles of treatment with 83-90.1% success rates.

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APA: Copy

TORABIZADEH, A., & VAHID ROUDSARI, FATEMEH. (2005). EVALUATING THE PREVALENCE OF HYPOGONADOTROPIC AMENORRHEA IN INFERTILE WOMEN AND THE RATE OF PREGNANCY FOLLOWING TREATMENT. JOURNAL OF REPRODUCTION AND INFERTILITY, 6(3 (23)), 247-253. SID. https://sid.ir/paper/28397/en

Vancouver: Copy

TORABIZADEH A., VAHID ROUDSARI FATEMEH. EVALUATING THE PREVALENCE OF HYPOGONADOTROPIC AMENORRHEA IN INFERTILE WOMEN AND THE RATE OF PREGNANCY FOLLOWING TREATMENT. JOURNAL OF REPRODUCTION AND INFERTILITY[Internet]. 2005;6(3 (23)):247-253. Available from: https://sid.ir/paper/28397/en

IEEE: Copy

A. TORABIZADEH, and FATEMEH VAHID ROUDSARI, “EVALUATING THE PREVALENCE OF HYPOGONADOTROPIC AMENORRHEA IN INFERTILE WOMEN AND THE RATE OF PREGNANCY FOLLOWING TREATMENT,” JOURNAL OF REPRODUCTION AND INFERTILITY, vol. 6, no. 3 (23), pp. 247–253, 2005, [Online]. Available: https://sid.ir/paper/28397/en

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