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Information Journal Paper

Title

Advanced Virtual Monochromatic Images from Dual Source Dual-Energy CT for a Reduction in the Contrast Medium Dose (389 mgI/kg) in Multiphase Liver CT: Evaluation of Image Quality and Focal Lesion Conspicuity

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Abstract

 Background: Low-energy advanced virtualmonochromaticimages (VMIs)from dual source Dual-Energy CT (DSCT) could be applied to reduce Contrast Medium dose due to superior iodine contrast-to-noise ratios (CNRs). Objectives: To investigate feasibility of advanced VMIs from DSCT to reduce Contrast Medium dose in multiphase liver CT without impairing image quality and conspicuity of focal hepatic lesions (FHLs). Patients and Methods: Ninety-four patients with 110 FHLs underwent follow-up CT twice prospectively with different protocols: protocol A, conventional 100 kVp and 555 mgI/kg; protocol B, Dual-Energy mode and 389 mgI/kg. The signal-to-noise ratio (SNR) and lesion-to-liver CNR were compared between the VMIs (40-120 keV, 10-keV interval) reconstructed using advanced image-based algorithm and conventional images. Two radiologists qualitatively evaluated VMIs, compared with the 100 kVp images, using a six-point scale. Results: The SNRs of pancreas, aorta, portal and hepatic vein were similar to those at 100 kVp images (P > 0. 05) at 40-50 keV images during late arterial phase (LAP) and at 40-60 keV images during portal venous phase (PVP) except for the SNRs of aorta and veins at 40 keV images which were significantly higher (P < 0. 0109) during both phases and PVP, respectively. The CNR of 56 hypervascular FHLs was significantly higher at 40-50 keV images (P < 0. 0002) and was similar at 60 keV images (P > 0. 05) during LAP. The CNR of 58 hypovascular FHLs was similar at 40-120 keV images (P > 0. 05) during PVP. Among the VMIs, 50 keV and 50-60 keV images received the highest scores (P < 0. 0315 and P < 0. 0041) by both reviewers during LAP and PVP, respectively. Conclusion: Advanced 50-60 keV images from DSCT allowed contrast dose reduction by 30% in multiphase liver CT without impairing image quality and conspicuity of FHLs, compared with the conventional 100 kVp images with 555 mgI/kg.

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    APA: Copy

    KIM, JI EUN, Kim, Hyun Ok, Bae, Kyungsoo, CHO, JAE MIN, CHOI, HO CHEOL, CHOI, DAE SEOB, & Na, Jaebeom. (2019). Advanced Virtual Monochromatic Images from Dual Source Dual-Energy CT for a Reduction in the Contrast Medium Dose (389 mgI/kg) in Multiphase Liver CT: Evaluation of Image Quality and Focal Lesion Conspicuity. IRANIAN JOURNAL OF RADIOLOGY, 16(3), 0-0. SID. https://sid.ir/paper/284802/en

    Vancouver: Copy

    KIM JI EUN, Kim Hyun Ok, Bae Kyungsoo, CHO JAE MIN, CHOI HO CHEOL, CHOI DAE SEOB, Na Jaebeom. Advanced Virtual Monochromatic Images from Dual Source Dual-Energy CT for a Reduction in the Contrast Medium Dose (389 mgI/kg) in Multiphase Liver CT: Evaluation of Image Quality and Focal Lesion Conspicuity. IRANIAN JOURNAL OF RADIOLOGY[Internet]. 2019;16(3):0-0. Available from: https://sid.ir/paper/284802/en

    IEEE: Copy

    JI EUN KIM, Hyun Ok Kim, Kyungsoo Bae, JAE MIN CHO, HO CHEOL CHOI, DAE SEOB CHOI, and Jaebeom Na, “Advanced Virtual Monochromatic Images from Dual Source Dual-Energy CT for a Reduction in the Contrast Medium Dose (389 mgI/kg) in Multiphase Liver CT: Evaluation of Image Quality and Focal Lesion Conspicuity,” IRANIAN JOURNAL OF RADIOLOGY, vol. 16, no. 3, pp. 0–0, 2019, [Online]. Available: https://sid.ir/paper/284802/en

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