PROSTATE IMRT: TWO-DIMENSIONAL MODEL OF RECTAL NTCP EMPLOYING THE VARIABILITY OF RECTAL MOTION AND RECTUM WALL THICKNESS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GRIGOROV GR.N.; FOSTER K.; CHOW J.C.L.; OSEI E.K.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Radiation Research Year:2014 | Volume:12 | Issue:4 Page(s): 283-293

Download Full-Text

View:

363

Download:

178

Cites:

Information Journal Paper

Title

PROSTATE IMRT: TWO-DIMENSIONAL MODEL OF RECTAL NTCP EMPLOYING THE VARIABILITY OF RECTAL MOTION AND RECTUM WALL THICKNESS

Author(s)

GRIGOROV GR.N. | FOSTER K. | CHOW J.C.L. | OSEI E.K. | Issue Writer Certificate

Keywords

PROSTATE IMRT

RECTAL MOTION

VARIABILITY OF THE RECTAL WALL THICKNESS

2D FIELD OF POSSIBLE RECTAL NTCPS

Abstract

Background: In order to improve the evaluation of possible rectal toxicity based on the rectal normal tissue complication probability (NTCP), we consider the fractional dependence of the NTCP on the wall thickness (tW) and rectal displacement (RM).Materials and Methods: The two‐dimensional NTCP model (NTCP2D) was developed using radiotherapy plans of ten randomly selected patients with prostate cancer. The clinical rectal structures were substituted with rectal walls of cylindrical shape. To simulate full, partially‐full and empty state of the rectum, three tW were generated under the conditions of same length of the rectum and same volume of the rectal wall. A threshold iso‐line, NTCPTR, was used to split the NTCP2D field into areas: a lower risk area and a higher risk area for rectal toxicity. Two factors are introduced to help with the estimation of NTCP: a volume factor k1 which is the ratio between the volumes of the rectal wall and the intersection of the rectal wall with the planning target volume; and a probability factor k2, which is the ratio between the area of low risk to the entire area of the NTCP2D.Results: A correlation>0.9 between factors k1 and k2 was found.Conclusion: The NTCP2D field and the ratios k1 and k2 can be used as a patient‐specific parameters to evaluate the probability of rectal toxicity.

Cites

No record.

References

No record.

Cite

APA: Copy

GRIGOROV, GR.N., FOSTER, K., CHOW, J.C.L., & OSEI, E.K.. (2014). PROSTATE IMRT: TWO-DIMENSIONAL MODEL OF RECTAL NTCP EMPLOYING THE VARIABILITY OF RECTAL MOTION AND RECTUM WALL THICKNESS. INTERNATIONAL JOURNAL OF RADIATION RESEARCH, 12(4), 283-293. SID. https://sid.ir/paper/286662/en

Vancouver: Copy

GRIGOROV GR.N., FOSTER K., CHOW J.C.L., OSEI E.K.. PROSTATE IMRT: TWO-DIMENSIONAL MODEL OF RECTAL NTCP EMPLOYING THE VARIABILITY OF RECTAL MOTION AND RECTUM WALL THICKNESS. INTERNATIONAL JOURNAL OF RADIATION RESEARCH[Internet]. 2014;12(4):283-293. Available from: https://sid.ir/paper/286662/en

IEEE: Copy

GR.N. GRIGOROV, K. FOSTER, J.C.L. CHOW, and E.K. OSEI, “PROSTATE IMRT: TWO-DIMENSIONAL MODEL OF RECTAL NTCP EMPLOYING THE VARIABILITY OF RECTAL MOTION AND RECTUM WALL THICKNESS,” INTERNATIONAL JOURNAL OF RADIATION RESEARCH, vol. 12, no. 4, pp. 283–293, 2014, [Online]. Available: https://sid.ir/paper/286662/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops