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Information Journal Paper

Title

PERCUTANEOUS MICROWAVE ABLATION OF THYROID NODULES: EFFICACY EVALUATION WITH 99M TC - PERTECHNETATE AND 99MTC-MIBI FUNCTIONAL IMAGING

Pages

  91-98

Keywords

99MTC-PERTECHNETATE SCINTIGRAPHY 
99MTC-MIBI SCINTIGRAPHY 

Abstract

 Background: Local ablave treatments play an important role for paents who cannot be treated surgically. Radiofrequency ablaon is a well-established alternave to surgical treatment of THYROID NODULES, however it also has disadvantages. Microwave ablaon (MWA) is a new minimally invasive treatment promising several improvements. The aim of this retrospecve study was to evaluate the effects of microwave ablaon on THYROID NODULES by99mTc-pertechnetate and 99mTc-MIBI scingraphy.Materials and Methods: 30 paents with overall 40 nodules were treated.For the ablaon of THYROID NODULES, a microwave generator working with frequencies from 902 to 928 MHz was used. The ablaon me ranged between 120 and 300 seconds per ablaon zone. The target temperatures ranged between 60-80oC. Pre- and post- intervenonal, the radionuclide uptake was determined using a thyroid specific scinllaon camera. For 27 cold nodules99mTc-MIBI was used for evaluaon; 13 indifferent nodules were measured with99mTc-pertechnetate.Results: The relave change of uptake was detected as a quoent of pre- and post- therapeuc uptake. The stascal analysis of scingraphy data proved the efficacy of microwave ablaon.99mTc-pertechnetate scingraphy showed an uptake reducon of 39% (range 9 to 85%).99mTc-MIBI imaging showed a median reducon of 40% (p<0.01) (range 7 to 100%).Conclusion: The determined results show the effecveness of MWA as a treatment opon for benign THYROID NODULES. With funconal scingraphy a significant acvity decrease could be detected in the ablaon zone; hence a verificaon of affecvity was possible a=er a short period of me.

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    APA: Copy

    HECK, KRISTINA, KORKUSUZ, Y., HAPPEL, C., GRUNWALD, F., & KORKUSUZ, H.. (). . , (), -. SID. https://sid.ir/paper/286703/en

    Vancouver: Copy

    HECK KRISTINA, KORKUSUZ Y., HAPPEL C., GRUNWALD F., KORKUSUZ H.. . [Internet]. ;():-. Available from: https://sid.ir/paper/286703/en

    IEEE: Copy

    KRISTINA HECK, Y. KORKUSUZ, C. HAPPEL, F. GRUNWALD, and H. KORKUSUZ, “,” , vol. , no. , pp. –, , [Online]. Available: https://sid.ir/paper/286703/en

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