STUDY ON THE EFFECT OF PALIURUS SPINA-CHRISTI ON CHOLESTEROL, TRIGLYCERIDE AND HDL LEVELS IN DIABETIC MALE RATS FED A HIGH CHOLESTEROL DIET

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MOSADEGH M.; KHOSHNOUD M.J.; KAMALINEZHAD M.; ALIZADEH E.

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Journal: Iranian Journal of Pharmaceutical Research Year:2004 | Volume:3 | Issue:1 Page(s): 51-54

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Title

STUDY ON THE EFFECT OF PALIURUS SPINA-CHRISTI ON CHOLESTEROL, TRIGLYCERIDE AND HDL LEVELS IN DIABETIC MALE RATS FED A HIGH CHOLESTEROL DIET

Author(s)

MOSADEGH M. | KHOSHNOUD M.J. | KAMALINEZHAD M. | ALIZADEH E. | Issue Writer Certificate

Keywords

HYPERCHOLESTEROLEMIA

TRIGLYCERIDE

STREPTOZOCIN

PALIURUS SPINA-CHRISTI

Abstract

Paliurus spina-christi Mill (Rhamnaceae) has been used in folk medicine as a hypocholesterolemic agent. In this study, the effect of total fruit extract on lowering lipid content of serum was investigated. Male rats were introduced STREPTOZOCIN, subsequently fed with a high cholesterol diet and concomitantly treated with various doses of the extract. After 8 days, serum levels of cholesterol, TRIGLYCERIDE and HDL were measured. It was found that the administration of 100 mg/kg/day of the extract had reduced the amount of total cholesterol by 45.5% and the administration of 50 mg/kg/day reduced the amount of TRIGLYCERIDE by 48.73%. No significant enhancement was found in the amount of HDL. It was concluded that of PALIURUS SPINA-CHRISTI extract can inhibit the enhancement of cholesterol and TRIGLYCERIDE

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APA: Copy

MOSADEGH, M., KAMALINEZHAD, M., KHOSHNOUD, M.J., & ALIZADEH, E.. (2004). STUDY ON THE EFFECT OF PALIURUS SPINA-CHRISTI ON CHOLESTEROL, TRIGLYCERIDE AND HDL LEVELS IN DIABETIC MALE RATS FED A HIGH CHOLESTEROL DIET. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 3(1), 51-54. SID. https://sid.ir/paper/287211/en

Vancouver: Copy

MOSADEGH M., KAMALINEZHAD M., KHOSHNOUD M.J., ALIZADEH E.. STUDY ON THE EFFECT OF PALIURUS SPINA-CHRISTI ON CHOLESTEROL, TRIGLYCERIDE AND HDL LEVELS IN DIABETIC MALE RATS FED A HIGH CHOLESTEROL DIET. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2004;3(1):51-54. Available from: https://sid.ir/paper/287211/en

IEEE: Copy

M. MOSADEGH, M. KAMALINEZHAD, M.J. KHOSHNOUD, and E. ALIZADEH, “STUDY ON THE EFFECT OF PALIURUS SPINA-CHRISTI ON CHOLESTEROL, TRIGLYCERIDE AND HDL LEVELS IN DIABETIC MALE RATS FED A HIGH CHOLESTEROL DIET,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 3, no. 1, pp. 51–54, 2004, [Online]. Available: https://sid.ir/paper/287211/en

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