SHORT COMMUNICATION: ANTILEISHMANIAL EFFECT OF ECHINACEA PURPUREA ROOT EXTRACT CULTIVATED IN IRAN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SOOUDI S.; HASHEMI S.M.; ZAVARAN HOSSEINI A.; GHAEMI AMIR; ASGHARI JAFARABADI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pharmaceutical Research Year:2007 | Volume:6 | Issue:2 Page(s): 145-147

Download Full-Text

View:

406

Download:

186

Cites:

Information Journal Paper

Title

SHORT COMMUNICATION: ANTILEISHMANIAL EFFECT OF ECHINACEA PURPUREA ROOT EXTRACT CULTIVATED IN IRAN

Author(s)

Keywords

ECHINACEA PURPUREA

EXTRACT

LEISHMANIA MAJOR

LEISHMANICIDAL ACTIVITY

Abstract

Due to the limited availability of effective pharmaceutical products and serious side effects of the available therapy for leishmaniasis, search for useful medicinal plants is necessary. Previous studies reported preventative effect of Echinacea against Leishmania infections through immunologic stimulation. Here we tested concentrated ethanolic EXTRACT of the root of ECHINACEA PURPUREA prepared from Zardband Pharmaceutical Co. for its direct LEISHMANICIDAL ACTIVITY in Leishmania culture. LEISHMANIA MAJOR promastigotes (stationary phase) were cultured in different concentrations of the EXTRACT (0.5–125 mg/ml) for 30 min. Then the EXTRACT was removed and cell viability was determined during 120 h. LD50 for the promastigotes were determined as 22.3, 16.7, 3.66, 1.98 and 1.23 mg at 8, 16, 24, 48 and 72 h respectively. The results showed the irreversible LEISHMANICIDAL ACTIVITY of the E. purpurea. Although all concentrations of the EXTRACT had antileishmanial effect, we suggest using this crude EXTRACT in concentrations of 50 mg/ml and more for application in related medicinal targets.

Cites

EVALUTION OF ANTILEISHMANIAL ACTIVITY OF THE HYDROALCOHLIC EXTRACT OF MEDICAGO LUPULINA' LEAVES AGAINST LEISHMANIA MAJOR (MHOM/IR/75/ER) PROMASTIGOTES BY USING MTT AND MICROSCOPY METHOD AND GC/MS FOR HYDROALCOHLIC EXTRACT OF THIS PLANT' LEAVES

References

No record.

Cite

APA: Copy

SOOUDI, S., HASHEMI, S.M., ZAVARAN HOSSEINI, A., GHAEMI, AMIR, & ASGHARI JAFARABADI, M.. (2007). SHORT COMMUNICATION: ANTILEISHMANIAL EFFECT OF ECHINACEA PURPUREA ROOT EXTRACT CULTIVATED IN IRAN. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 6(2), 145-147. SID. https://sid.ir/paper/287624/en

Vancouver: Copy

SOOUDI S., HASHEMI S.M., ZAVARAN HOSSEINI A., GHAEMI AMIR, ASGHARI JAFARABADI M.. SHORT COMMUNICATION: ANTILEISHMANIAL EFFECT OF ECHINACEA PURPUREA ROOT EXTRACT CULTIVATED IN IRAN. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2007;6(2):145-147. Available from: https://sid.ir/paper/287624/en

IEEE: Copy

S. SOOUDI, S.M. HASHEMI, A. ZAVARAN HOSSEINI, AMIR GHAEMI, and M. ASGHARI JAFARABADI, “SHORT COMMUNICATION: ANTILEISHMANIAL EFFECT OF ECHINACEA PURPUREA ROOT EXTRACT CULTIVATED IN IRAN,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 6, no. 2, pp. 145–147, 2007, [Online]. Available: https://sid.ir/paper/287624/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops