THE STABILITY STUDIES OF PENICILLIN AND AMPICILLIN FOLLOWING γ-IRRADIATION IN THE SOLID STATE

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BETESHOBABRUD R.; NABARDI F.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pharmaceutical Research Year:2009 | Volume:8 | Issue:3 Page(s): 153-157

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Information Journal Paper

Title

THE STABILITY STUDIES OF PENICILLIN AND AMPICILLIN FOLLOWING γ-IRRADIATION IN THE SOLID STATE

Author(s)

BETESHOBABRUD R. | NABARDI F. | Issue Writer Certificate

Keywords

γ-IRRADIATION

STERILIZATION

PENICILLIN

AMPICILLIN

STABILITY

SAL

Abstract

The effect of 10 and 25 kGy g-irradiation on PENICILLIN G plus procaine and sodium AMPICILLIN has been assessed by different chemical and microbiological analytical methods. According to the chemical results obtained, the antibiotics showed a slight reduction in doses applied but the microbiological assays revealed that the activity of irradiated antibiotics did not reduce. Microbiological studies were carried out in order to determine the minimum absorbed dose required to achieve Sterility Assurance Level (SAL) of 10-6. Briefly, lower irradiation doses seem to be useful for decontamination purposes.

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APA: Copy

BETESHOBABRUD, R., & NABARDI, F.. (2009). THE STABILITY STUDIES OF PENICILLIN AND AMPICILLIN FOLLOWING γ-IRRADIATION IN THE SOLID STATE. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 8(3), 153-157. SID. https://sid.ir/paper/287727/en

Vancouver: Copy

BETESHOBABRUD R., NABARDI F.. THE STABILITY STUDIES OF PENICILLIN AND AMPICILLIN FOLLOWING γ-IRRADIATION IN THE SOLID STATE. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2009;8(3):153-157. Available from: https://sid.ir/paper/287727/en

IEEE: Copy

R. BETESHOBABRUD, and F. NABARDI, “THE STABILITY STUDIES OF PENICILLIN AND AMPICILLIN FOLLOWING γ-IRRADIATION IN THE SOLID STATE,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 8, no. 3, pp. 153–157, 2009, [Online]. Available: https://sid.ir/paper/287727/en

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