MUSHROOMS AS POSSIBLE ANTIOXIDANT AND ANTIMICROBIAL AGENTS

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KOSANIC MARIJANA; RANKOVIC BRANISLAV; DASIC MARKO

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Journal Paper

Paper Information

Journal: Iranian Journal of Pharmaceutical Research Year:2012 | Volume:11 | Issue:4 Page(s): 1095-1102

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Information Journal Paper

Title

MUSHROOMS AS POSSIBLE ANTIOXIDANT AND ANTIMICROBIAL AGENTS

Author(s)

KOSANIC MARIJANA | RANKOVIC BRANISLAV | DASIC MARKO | Issue Writer Certificate

Keywords

MUSHROM EXRACTS

ANTIOXIDANT ACTIVITY

ANTIMICROBIAL ACTIVITY

Abstract

The aim of the study is to examinein-vitro antioxidant and ANTIMICROBIAL ACTIVITY of the acetonic and methanolic extracts of the mushrooms Boletus aestivalis, Boletus edulis and Leccinum carpini. ANTIOXIDANT ACTIVITY was evaluated by using free radical scavenging activity and reducing power. In addition, total content of phenol and flavonoid in extracts were determined as pyrocatechol equivalent, and as rutin equivalent, respectively. As a result of the study acetonic extracts from Boletus edulis was more powerful ANTIOXIDANT ACTIVITY with IC50 value of 4.72 mg/mL which was similar or greater than the standard antioxidants, ascorbic acid (IC50=4.22 mg/mL), BHA (IC50=6.42 mg/mL) and a-tocopherol (IC50=62.43 mg/mL). Moreover, the tested extracts had effective reducing power. A significant relationship between total phenolic and flavonoid contents and their antioxidative activities was significantly observed. The ANTIMICROBIAL ACTIVITY of each extract was estimated by determination of the minimum inhibitory concentration by using microdilution plate method against five species of bacteria and five species of fungi. Generally, the tested mushroom extracts had relatively strong ANTIMICROBIAL ACTIVITY against the tested microorganisms. The minimum inhibitory concentration for both extracts related to the tested bacteria and fungi were 1.25-10 mg/mL. The present study shows that tested mushroom species demonstrated a strong antioxidant and ANTIMICROBIAL ACTIVITY. It suggests that mushroom may be used as good sources of natural antioxidants and for pharmaceutical purposes in treating of various diseases.

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APA: Copy

KOSANIC, MARIJANA, RANKOVIC, BRANISLAV, & DASIC, MARKO. (2012). MUSHROOMS AS POSSIBLE ANTIOXIDANT AND ANTIMICROBIAL AGENTS. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 11(4), 1095-1102. SID. https://sid.ir/paper/288037/en

Vancouver: Copy

KOSANIC MARIJANA, RANKOVIC BRANISLAV, DASIC MARKO. MUSHROOMS AS POSSIBLE ANTIOXIDANT AND ANTIMICROBIAL AGENTS. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2012;11(4):1095-1102. Available from: https://sid.ir/paper/288037/en

IEEE: Copy

MARIJANA KOSANIC, BRANISLAV RANKOVIC, and MARKO DASIC, “MUSHROOMS AS POSSIBLE ANTIOXIDANT AND ANTIMICROBIAL AGENTS,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 11, no. 4, pp. 1095–1102, 2012, [Online]. Available: https://sid.ir/paper/288037/en

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